If the excised, parturient rabbit uterus is repeatedly treated with a Krebs solution free from Ca, its tension in a tetanus drops gradually, and in 15 to 30 minutes becomes zero. We call such a uterus "Ca-deficient." The uterus in this condition has a high threshold, it is non-propagating, "inexcitable," fails to respond to oxytocics in a characteristic fashion, but retains maximum contractilit...

Female reproductive organs are mainly regulated by estrogen and progesterone. Specifically, the uterus, vagina and mammary gland show organ-specific mitosis and morphological changes during proliferative events, such as estrous cycle, gestation and lactation. The mechanism underlying these organ-specific estrogen-dependent events is still unknown. We examined, therefore, global gene expression ...

background: the luteal phase defect is a common event following the ovarian stimulation. the aim of the present study was to evaluate the use of human chorionic gonadotropine (hcg) and progesterone hormones to improve the luteal phase defect. materials and methods: 60 mice were superovulated routinely with human menopausal gonadotropin (hmg) (7.5u) and hcg (10u). the mice were mated and divided...

August 18, 2017 Type Package Title Evaluation of Surrogate Endpoints in Clinical Trials Version 0.4 Date 2017-08-18 Author Wim Van der Elst, Paul Meyvisch, Ariel Alonso, Hannah M. Ensor, Christopher J. Weir & Geert Molenberghs Maintainer Wim Van der Elst Description In a clinical trial, it frequently occurs that the most credible outcome to evaluate the effectiveness ...

Before we apply nonlinear techniques, for example those inspired by chaos theory, to dynamical phenomena occurring in nature, it is necessary to rst ask if the use of such advanced techniques is justiied by the data. While many processes in nature seem very unlikely a priori to be linear, the possible nonlinear nature might not be evident in speciic aspects of their dynamics. The method of surr...

UNLABELLED Uterine incarceration is an uncommon but serious presentation in the emergency department that requires early recognition to improve maternal and fetal outcomes. CASE A 29-year-old female, at 12 weeks gestation, presented to the emergency department (ED) with complaints of fever, sacral pain and urgency. Based on history and physical examination, she was found to have a retroverted...

Uterus didelphys with obstructed hemivagina and ipsilateral renal agenesis (OHVIRA Syndrome) is a rare congenital anomaly of the female genital tract. Uterus didelphys occurs when the midline fusion of the mullerian ducts is arrested, either completely or incompletely. Women with didelphic uterus may be asymptomatic and unaware of having a double uterus. They may present with complaints of dysm...

Congenital anomalies of the Müllerian ducts especially uterine abnormalities can affect negatively the different stages of fertility interfering with sperm migration, embryo implantation, normal placentation, fetal growth and achievement of a successful pregnancy. They are present in 2-10% of all women, three times greater in patients with recurrent pregnancy loss and lead to infertility and ad...

Uterus mullerian adenosarcoma is a very rare malignancy. The clinical and Ultra Sonographic findings are not exclusive and the histomorphologic diagnosis of low-grade adenosarcomas is not straightforward. Herein, we present a young Iranian woman with menometrorrhagia due to exceptional occurrence of uterus Mullerian adenosarcoma. A 24-year-old woman, with menometrorrhagia was referred. Imaging...