During phagocytosis of opsonized lipopolysaccharide-coated paraffin oil droplets, rabbit alveolar macrophages reduced nitroblue tetrazolium, which effect was in part inhibitable with the use of superoxide dismutase. Exposure of cytochalasin-B-treated rabbit alveolar macrophages to opsonized zymosan led to the generation of superoxide, as quantitated by ferricytochrome C reduction. It was found ...

In sustained severe ischemia, reperfusion with oxygen carriers may result in ischemia-reperfusion injuries because of the release of damaging oxygen radicals. A nanobiotechnology-based polyhemogloin-calatase-superoxide dismutase can prevent this because the oxygen carrier, polyhemoglobin, is linked to antioxidant enzymes, catalase and superoxide dismutase. However, these antioxidant enzymes com...

Grant Title: The Protective Roles of the Antioxidant Enzymes Superoxide Dismutase and Catalase in the Green Photosynthetic Bacterium Chlorojlexus aurantiacus . Supervisors: Robert E. Blankenship, Arizona State University Lynn Rothschild, NASA Ames Research Center Grant Number: NGT 2-52284 Grant Period: August 2000 August 2003 Publication: Lancaster, V.L., R. LoBrutto, F. Selvaraj, R.E. Blankens...

Copperand zinc-containing Superoxide dismutase, man ganese-containing Superoxide dismutase, catalase, and glutathione peroxidase form the primary enzymic defense against toxic oxygen reduction metabolites. Such metabolites have been implicated in the damage brought about by ionizing radiation, as well as in the effects of several cytostatic com pounds. These enzymes were analyzed in 31 differen...

background: superoxide radicals are produced during oxidative metabolic processes, and removed by superoxide dismutase (sod) enzymes. controversial results have been reported regarding the tissue and plasma concentration of sod in patients with breast cancer. methods: venous blood was obtained from study participants and activity of sod enzyme was determined in 100 women. comparison was made be...