نتایج جستجو برای: sulforaphane

تعداد نتایج: 1372  

Journal: :Chemical Research in Toxicology 2011

Journal: :Annals of Oncology 2023

Gastric cancer (GC) is a disease with high incidence in the mountainous populations of Andes Nariño-Colombia (150/100,000) without changing last 20 years. The most important risk factor for development Helicobacter pylori infection, which affects more than 80% Colombian population. In Department Nariño-Colombia, eradication only strategy prevention gastric cancer. However, failure therapeutic a...

Journal: :Journal of Agribusiness and Agritourism 2023

Microgreens menjadi inovasi baru dalam pertanian di perkotaan. Kubis bunga ialah salah satu tanaman sayur yang dapat dibudidayakan secara microgreens. kubis mengandung sulforaphane merupakan senyawa golongan isothiocyanate, berpotensi sebagai anti kanker. Konsentrasi ini berubah sesuai kondisi lingkungan tumbuh, seperti media tanam dan ketersediaan nutrisi. Penelitian bertujuan untuk mendapatka...

2015
Cheng-Cao Sun Shu-Jun Li De-Jia Li

Sulforaphane (SFN) possesses powerful chemo-preventive effects and plays a crucial role on oxidative stress and inflammatory. In our recent study, SFN treatment could relieve muscular dystrophy in mdx mice by activating Nrf2 (NF-E2 related factor 2). Moreover, our findings indicated that SFN-activated Nrf2 alleviated muscle inflammation in dystrophin-deficient mdx mice through suppressing NF-κB...

Journal: :Bioorganic & medicinal chemistry letters 2015
Sarah M Lewis Ya Li Michael J Catalano Adrian R Laciak Harkewal Singh Derrick R Seiner Thomas J Reilly John J Tanner Kent S Gates

Isothiocyanates are bioactive dietary phytochemicals that react readily with protein thiol groups. We find that isothiocyanates are time-dependent inactivators of cysteine-dependent protein tyrosine phosphatases (PTPs). Rate constants for the inactivation of PTP1B and SHP-2 by allyl isothiocyanate and sulforaphane range from 2 to 16 M(-1)s(-1). Results in the context of PTP1B are consistent wit...

Journal: :Current Developments in Nutrition 2020

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