The therapeutic management of symptomatic uterine fibroids is based on three pillars: surgery, pharmacotherapy, and interventional radiotherapy. Modern myoma treatment is personalised and should involve an interdisciplinary approach according to the patient’s wishes and pathology.

Identifying and resecting gastric submucosal lesions through submucosal tunneling is not always easy, because of difficulties in orientation or a lack of sufficient working space. This article presents the resection of two gastric lipomas with a modified pocket-creation method (Fig. 1), initially scheduled for endoscopic submucosal dissection (ESD) of epithelial lesions [1]. A 63-year-old male ...

Hyperemesis gravidarum can cause various vitamin deficiencies. Vitamin K deficiency can lead to coagulopathy or hemorrhagic diathesis. A nulliparous Japanese woman with hyperemesis gravidarum at 10(5/7) weeks was admitted with giant myoma, intestinal obstruction, and abdominal pain. Treatment for a degenerative myoma was instituted with intravenous antibiotics. The abdominal pain ameliorated, b...

PROBLEM To explore the roles of leptin, monocyte chemotactic protein (MCP)-1, and tumour necrosis factor (TNF)-α in the peritoneal fluid (PF) in the pathogenesis of endometriosis-associated infertility. METHOD OF STUDY Leptin, MCP-1, and TNF-α levels in the PF from 28 infertile women with endometriosis (study group), 23 women with fallopian-associated infertility (controls), and 24 women with...

Leiomyomas are common benign uterine tumors. However, the incidence of vaginal myoma is very rare and may be confused with a variety of vaginal tumors. We report a case of 43-year-old nulligravida who presented with a protruding painful vaginal mass for 7 days. The mass had initially appeared 3 years prior, as 2 to 3 cm that had not subsequently increased. However suddenly, there was rapid seve...

INTRODUCTION Primary adenocarcinomas resembling submucosal tumors are rare in the gastrointestinal tract. Almost all the submucosal tumor-like adenocarcinomas previously reported invaded the submucosa or deeper. Therefore, submucosal tumor-like lesions are usually treated by surgical resection, and those that arise in the duodenum have been treated by pancreaticoduodenectomy. CASE PRESENTATIO...

The endoscopic examination of a 64-year-old male patient revealed a gastric submucosal tumor in the anterior wall of the gastric antrum. The lesion increased in diameter to 25 mm and was resected completely with endoscopic submucosal dissection (ESD). Histological examination of the submucosal tumor gave a diagnosis of an inflammatory fibroid polyp (IFP). It is suggested that ESD may be an effe...

background: in fertile women, glycodelin and glutathione peroxidase 3 (gpx3) genes expression rises during the luteal phase, with a peak occurring during the implantation window. the expression of these genes decreases in women with myomas. to determine whether myomectomy would reverse glycodelin and gpx3 expression, we evaluated the transcript levels of these genes in the endometrium of patien...