An 85 year male patient complaining epigastric discomfort was admitted. From the esophagogastroduodenoscopy, three early gastric cancer (EGCa) lesions had been identified and these were diagnosed as adenocarcinoma with poorly differentiated cell type. The patient underwent operation. From the post-operative mapping, however, additional 4 EGCa lesions were found, and the patient was diagnosed wi...

The aim of the study was to investigate the relationship between the fibrous interstitium found in the spaces between tumor nests and the growth and proliferation process in 33 rectal carcinoid lesions (26 resected endoscopically and 7 resected surgically).The proportion of the tumor occupied by fibrous interstitium (F/T ratio) was measured in tissue specimens using an image analyzer, and the c...

Background: A single-operator, articulating, through-the-scope (TTS) traction device was recently developed to facilitate endoscopic submucosal dissection (ESD). Clinical data on the performance of this is limited. We report an initial multicenter experience ESD using articulating TTS device. Methods: Retrospective analysis all consecutive patients who underwent (T-ESD) at 5 centers between Aug...

This review consists of 6 sections: (1) pathological diversity of cancer and the correlation between 'zokushutsu' (budding/sprouting) and lymph node metastasis; (2) genetic analysis and metastasis in the gastrointestinal tract; (3) conditions requiring resection after endoscopic treatment; (4) improvement of methods used to measure depth of submucosal invasion in the Ip type; (5) Japanese morph...

Gastric hyperplastic polyps are generally considered benign lesions, although rare cases of adenocarcinoma have been reported. Although, the underlying mechanism of carcinogenesis in gastric hyperplastic polyps is still uncertain, most malignant polyps are seen to originate from dysplastic epithelium rather than from hyperplastic epithelium. Herein, we report the case of a woman diagnosed with ...

A 45-year-old male patient had left sided submucosal swelling extending backwards from the tip of the tongue disturbing articulation and swallowing. Submucosally located lesion was 3 x 2 x 1.5 cm in size and totally excised under local anesthesia. In this article, we present a case of ancient schwannoma of tongue. Although a very rare entity, ancient schwannoma should be considered in different...

Superficial spreading early gastric cancer (EGC) is a rare disease that is treated mainly by surgery. There are few studies on the safety of endoscopic treatment for patients with superficial spreading EGC. The aims of this study were to (1) investigate the risk of lymph node metastasis of superficial spreading EGC and (2) investigate the potential criteria for endoscopic treatment of superfici...

Background With the development of endoscopic technology, detection rate synchronous multiple primary early esophageal cancer (SMPEEC) is increasing; however, risk factors remain unclear. We aimed to assess clinicopathological characteristics patients with SMPEEC and investigate contributing lesions. Methods A retrospective cohort study was conducted on 911 consecutive who underwent Endoscopic ...