In vitro studies of tircarcillin or cefsulodin combined with [3H]tobramycin were performed with Pseudomonas aeruginosa. The rate of bacterial killing, the uptake of tobramycin, and the effects on optical density were measured. Both beta-lactams increased the uptake of subinhibitory concentrations of tobramycin. This result was quantitatively associated with a 2- to 4-h time-kill potentiation an...

We encountered a case of native valve endocarditis due to Corynebacterium CDC group I1 which was successfully controlled with antimicrobial agents alone. This organism and three other isolates of this group were susceptible to penicillin, vancomycin, and gentamicin. The combination of penicillin with subinhibitory concentrations of gentamicin resulted in a 1,000-fold decrease in CFU per millili...

Essential oils (EO) are a great antimicrobial resource against bacterial resistance in public health. Math models useful describing the growth, survival, and inactivation of microorganisms antimicrobials. We evaluated activity Melaleuca armillaris EO obtained from plants placed province Buenos Aires (Argentina) Staphylococcus aureus. The minimum inhibitory bactericidal concentrations were close...