Poor penetration of diclofenac through in vitro rat dorsal skin including subcutaneous tissue was observed. The poor penetration of diclofenac seemed to be predominIntly due to the poor permeability of the stratum corneum. Hydrogenated soya phospholipids (phospholipid) in aqueous gel form increased the penetration of diclofenac in the in vitro study, by increasing diclofenac transport through t...

OBJECTIVE To profile the differential gene expression of the KEGG Adipocytokine Signaling pathway in omental compared to subcutaneous tissue in normal pregnancy. STUDY DESIGN Subjects included 14 nonobese, normal glucose tolerant, healthy pregnant women. Matched omental and subcutaneous tissue were obtained at elective cesarean delivery. Gene expression was evaluated using microarray and vali...

introduction: the purpose of this study was to compare the subcutaneous tissue responses of freshly mixed or set endodontic root canal sealers ( i.e. roekoseal, ah26, ah plus) in wistar albino rats. materials and methods: seventy-two male albino rats weighing 200-250g were used. the animals were randomly divided into six groups of 12 rats each. root canal sealers were implanted in subcutaneous ...

introduction: the purpose of this study was to compare the histocompatibility of white (wmta) and gray (gmta) mineral trioxide aggregate mixed with 0.12% chlorhexidine (chx) and distilled water (dw) in subcutaneous connective tissues of rats. materials and methods: the freshly mixed wmta and gmta with chx or dw were inserted in polyethylene tubes and implanted into dorsal subcutaneous connectiv...

BACKGROUND The blood flow capacity in subcutaneous adipose tissue in humans remains largely unknown, and therefore the aim of this study was to determine the physiological range of blood flow in this tissue. METHODS AND RESULTS The subcutaneous adipose tissue blood flow (ATBF) was measured in 9 healthy young men by positron emission tomography using radiowater tracer. Subcutaneous ATBF was de...

Subcutaneous penile insertion of foreign bodies is a practice performed globally but has mostly been reported outside of the United States. An incarcerated 29-year-old Caucasian male in a midwestern prison whittled a domino into a dog bone shape and placed it into his ventral penile subcutaneous tissue. He presented to our facility with erosion of the corners of the foreign body through his ski...

Apomorphine hydrochloride is used to treat refractory motor fluctuations in advanced Parkinson’s disease. Delivery by infusion is associated with the formation of hard subcutaneous nodules, which may be painful, limit available infusion sites, and interfere with absorption of the drug. Diagnostic ultrasound was used to image affected tissue in 12 people experiencing apomorphine nodule formation...

The aim of this study was to characterize the tissue-associated differences in the fatty acid profiles of intramuscular, subcutaneous and hepatic lipids and their quality indices from Lithuanian indigenous wattle pig and wild boar backcross to lean breed. The samples from hybrid pigs (1/4 Lithuanian indigenous wattle, 1/4 wild boar and 1/2 Landrace) were used in the experiment. There was little...

The white adipose organ is composed of both subcutaneous and several intra-abdominal depots. Excess abdominal adiposity is a major risk factor for metabolic disease in rodents and humans, while expansion of subcutaneous fat does not carry the same risks. Brown adipose produces heat as a defense against hypothermia and obesity, and the appearance of brown-like adipocytes within white adipose tis...

A 72-year-old female presented rapidly developing ischemia of the skin and subcutaneous tissue antero-medial aspect a thigh. An atypical clinical manifestation led to delayed diagnosis treatment that resulted in development large loss anteromedial Endovascular recanalization recurrent occlusion ilio-femoral segment with rotational thrombectomy together multi-step local surgical healing lesion.