Primary cutaneous signet ring cell carcinoma (PCSRCC) is a very unusual but distinctive clinicopathologic entity that can simulate metastatic adenocarcinomas. It is defined as a diffuse malignant epithelial neoplasia localized in the dermis and subcutis without epidermal involvement, showing variable amounts of signet ring cells, without evidence of visceral adenocarcinoma. We present 2 cases o...

let $r$ be a ring‎, ‎and let $n‎, ‎d$ be non-negative integers‎. ‎a right $r$-module $m$ is called $(n‎, ‎d)$-projective if $ext^{d+1}_r(m‎, ‎a)=0$ for every $n$-copresented right $r$-module $a$‎. ‎$r$ is called right $n$-cocoherent if every $n$-copresented right $r$-module is $(n+1)$-coprese-nted‎, ‎it is called a right co-$(n,d)$-ring if every right $r$-module is $(n‎, ‎d)$-projective‎. ‎$r$ ...

True aneurysms of the digital artery are very rare. Only 13 cases, caused by chronic trauma from occupational or sports-related overuse, have been reported. We present the first case of a true aneurysm of the digital artery of the left ring finger caused by chronic repetitive trauma from a wedding ring. The patient was a 44-year-old teacher who presented with a 1.5-cm subcutaneous mass on the r...

1. McCullough PA. Contrast‐induced acute kidney injury. J Am Coll Cardiol 2008;51:1419‐28. 2. Mercer JB, Ring EF. Fever screening and infrared thermal imaging: Concerns and guidelines. Thermology Int 2009;19:67‐99. 3. Urakov AL, Kasatkin AA, Urakova NA, Ammer K. Infrared thermographic investigation of fingers and palms during and after application of cuff occlusion test in patients with hemorrh...

The ilioinguinal nerve was dissected in 196 adult human cadavers. A normal pattern of distribution, consistent with modern textual descriptions, was defined in 60% of inguinal regions. In 35% of the inguinal regions a previously undescribed aberrant course for the cutaneous component of the ilioinguinal nerve was observed in which it is incorporated within the genitofemoral nerve, entered the i...

the zero-divisor graph of a commutative ring r with respect to nilpotent elements is a simple undirected graph $gamma_n^*(r)$ with vertex set z_n(r)*, and two vertices x and y are adjacent if and only if xy is nilpotent and xy is nonzero, where z_n(r)={x in r: xy is nilpotent, for some y in r^*}. in this paper, we investigate the basic properties of $gamma_n^*(r)$. we discuss when it will be eu...

Dependence of the hydrolysis rate a series N-methoxy-2-phenyl-1,3-oxazinanes on Hammett substituent constant phenyl ring was determined, yielding reaction ρ=−1.40±0.05. Based this information, 4-(benzoyloxy)benzaldehyde selected as protecting group for new (2R,3S)-4-(methoxyamino)butane-1,2,3-triol phosphoramidite building block. The yield preparation block well its coupling in automated oligon...

The bacterial cell division protein FtsZ assembles into the cytokinetic Z ring that directs cytokinesis in prokaryotes. In Escherichia coli the formation of the Z ring is prevented by induction of the cell division inhibitor SulA (SfiA), a component of the SOS response. Here we show that a MalE-SulA fusion that retains this inhibitory function in vivo inhibits the GTPase activity and polymeriza...

We designed, fabricated, and characterized a monolithically integrated optofluidic ring resonator laser that is mechanically, thermally, and chemically robust. The entire device, including the ring resonator channel and sample delivery microfluidics, was created in a block of fused-silica glass using a 3-dimensional femtosecond laser writing process. The gain medium, composed of Rhodamine 6G (R...

Continuing our structure-activity studies on the vitamin D analogs with the altered intercyclic seco-B-ring fragment, we designed compounds possessing dienyne system conjugated with the benzene D ring. Analysis of the literature data and the docking experiments seemed to indicate that the target compounds could mimic the ligands with a good affinity to the vitamin D receptor (VDR). Multi-step s...