purpose: to determine the prevalence of various types of conjunctival lesions, at a tertiary ophthalmic center in fars province, south of iran. methods: histopathologic slides and medical records of conjunctival lesions submitted to the pathology department of khalili hospital, shiraz, iran was reviewed from april, 2009 to july, 2013. the histopathologic diagnoses were categorized into benign, ...

purpose: a 12 year-old boy and a known case of job’s syndrome presented with a large conjunctival mass which represented coexistence of hpv and hsv infections. case report: the presence of hpv virus within these lesions was confirmed by biopsy and dna analysis. the mass lesions did not respond to anti-hpv therapy with topical interferon-α2b, oral cimetidine and oral acyclovir, but improved prom...

purpose : to evaluate the efficiency and safety of using autologous fibrin glue for attachment of a conjunctival autograft in primary pterygium surgery methods : in this prospective interventional case series, 15 eyes from 13 patients with primary nasal pterygium were included for conjunctival autograft surgery. on the operation day, thrombin and fibrinogen were prepared from the patient’s own ...

Ligneous conjunctivitis is a type of chronic characterized by the presence pseudomembranes on conjunctival surface. It can present as part multisystem disease with involvement other mucous membranes. A 1-year-old girl presented features conjunctivitis. Local examination revealed thick exudates in left tarsal conjunctiva, which was diagnosed an ulcer pseudomembrane and sterile culture. The patie...

In our recently published study (1), we describe genetic similarities between conjunctival and cutaneousmelanoma and propose that the treatment rationale for patients with metastasized conjunctival melanoma should be adapted to that for metastasized cutaneous melanoma. Weber and colleagues (2) responded to this, reporting that a BRAF V600E–mutant metastasized conjunctival melanoma patient treat...

We previously reported that EP3, a subtype of prostaglandin E2 receptors, negatively regulates eosinophilic infiltration in murine experimental allergic conjunctivitis induced by TLR3, which causes reduced eosinophilic conjunctival inflammation in TLR3/EP3 double knockout (DKO) mice although in EP3-KO mice eosinophilic conjunctival inflammation is pronounced. We also documented that in human co...

BACKGROUND To investigate the incidence, risk factors and survival of conjunctival acute graft-versus-host disease (aGVHD) in adult patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT). METHODS This retrospective study included a total of 139 patients undergoing allogeneic HSCT between January 2012 and December 2014 at a tertiary referral hospital. Patients with ocula...

BACKGROUND In our earlier genome-wide association study on Stevens-Johnson Syndrome (SJS) and its severe variant, toxic epidermal necrolysis (TEN), we found that in Japanese patients with these severe ocular surface complications there was an association with prostaglandin E receptor 3 (EP3) gene (PTGER3) polymorphisms. We also reported that EP3 is dominantly expressed in the ocular surface-, e...

PURPOSE In the field of ophthalmology, the conjunctival autograft is a useful therapeutic material in many cases, but the small size of the autograft is a disadvantage. Therefore, we evaluated the feasibility of taking an expanded sample of conjunctival tissue using a subtenon's silicone implant. MATERIALS AND METHODS We included a total of nine rabbits; eight rabbits were operative cases, an...

Purpose: Ocular neoplasms, both primary and metastatic, may present with visual disturbance or vision loss often are asymptomatic. Clinical examination demonstrate leukocoria, abnormal pupillary light reflex, a mass lesion without retinal detachment hemorrhage. Retinoblastoma in children uveal melanoma ocular metastases adults the most important malignant neoplasms referred for imaging to aid d...