Background/Objective: Hyperphosphatemia is the consequence of end stage renal failure. Inadequate control of serum phosphorus results in elevated Ca×P product with subsequent soft tissue deposition in the form of conjunctival and corneal calcification.  In this study, we evaluated the relationship of conjunctival and corneal calcification with secondary hyperparathyroidism in hemodialysis patie...

Thickening of the ligamenta flava with and without ossification in the thoracic and lumbar regions is a frequent finding on CT scanning; however, it is not widely appreciated as a possible primary cause of compressive cord, cauda equina, and nerve-root symptoms. We present observations from a series of seven patients whose symptoms were caused exclusively or largely by thickened ligamenta flava...

introduction: aim of this study was to assess the association between prostate calcification in transrectalultrasound (trus) and sono- guided needle biopsy in prostate cancer (pca). methods: a cross-sectional study was performed on patients referred to imam khomeini hospital between 2005 and 2011 who underwent trus biopsy due to increased psa or abnormal dre. the serum levels of psa, prostate v...

We investigated the spectrum of lesions characteristic of post-traumatic osteoarthritis (PTOA) across the knee joint in response to mechanical injury. We hypothesized that alteration in knee joint stability in mice reproduces molecular and structural features of PTOA that would suggest potential therapeutic targets in humans. The right knees of eight-week old male mice from two recombinant inbr...

CASE REPORT A 45-year-old man presented to the Department of Medicine at our institution with 1 year of noninflammatory pain in multiple joints. The pain had begun in both knee joints, followed by low-back ache and neck, wrist, and foot pain. There was no associated fever or swelling of any joint. The patient did not report any history of addiction or illness but did report using fluoridated to...

Study Design Narrative review. Objective To provide an overview on the diagnosis, natural history, and nonoperative and operative management of ossification of the posterior longitudinal ligament (OPLL). OPLL is a multifactorial condition caused by ectopic hyperostosis and calcification of the posterior longitudinal ligament. Familial inheritance and genetic factors have been implicated in the ...

INTRODUCTION Two of the most common causes of anterior cervical bony outgrowths are diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS). These osteophytes have been associated with serious complications. The objective of this case report is to highlight how commonly occurring anterior cervical osteophytes may become an uncommon cause for life-threatening dysphagia an...

Periodontitis is an inflammatory disease causing loss of tooth-supporting periodontal tissue. Disease susceptibility to the rapidly progressive form of periodontitis, aggressive periodontitis (AgP), appears to be influenced by genetic risk factors. To identify these in a Japanese population, we performed whole exome sequencing of 41 unrelated generalized or localized AgP patients. We found that...

Introduction: Peripheral ossifying fibroma (POF) is a common solitary gingival overgrowth thought to arise from the gingival corium, periosteum and periodontal ligament (PDL). Commonly used synonyms for POF include calcifying fibroblastic granuloma, peripheral fibroma with calcification, peripheral cementifying fibroma, and calcifying or ossifying fibrous epulis. Case Report: This article prese...