The SureChEMBL database provides open access to 17 million chemical entities mentioned in 14 patents published since 1970. However, alongside with molecules covered by patent claims, the is full of starting materials and intermediate products little pharmacological relevance. Herein, we introduce a new filtering protocol automatically select core structures best representing congeneric series p...

Limiting identification of r.e. indexes for r.e. languages (from a presentation of elements of the language) and limiting identification of programs for computable functions (from a graph of the function) have served as models for investigating the boundaries of learnability. Recently, a new approach to the study of “intrinsic” complexity of identification in the limit has been proposed. This a...

The tremor injury is one of the common symptoms of Parkinson's disease. The patients suffering from Parkinson's disease have difficulty in controlling their movements owing to tremor. The intensity of the disease can be determined through specifying the range of intensity values of involuntary tremor in Parkinson patients. The level of disease in patients is determined through an empirical rang...

MOTIVATION So far various bioinformatics and machine learning techniques applied for identification of sequence and functionally conserved residues in proteins. Although few computational methods are available for the prediction of structurally conserved residues from protein structure, almost all methods require homologous structural information and structure-based alignments, which still prov...

This paper, presents a novel identification approach using fuzzy neural networks. It focuses on structure and parameters uncertainties which have been widely explored in the literatures. The main contribution of this paper is that an integrated analytic framework is proposed for automated structure selection and parameter identification. A kernel smoothing technique is used to generate a model ...

Synthesis, identification and thermal behavior studies of nanoparticles cobalt (II) bromide has been studied in this research. Cobalt (II) bromide was synthesized by planetary high-energy ball mill. The general formula of this compound is CoBr2.6H2O. The synthesized nanoparticles were characterized by Fourier transform infrared spectroscopy and also Size and structure of s...

Model identification of polynomial NARX models involves a lengthy and computationally intensive procedure for selecting the model structure among a possibly large set of candidate regressors. If the model structure is under-parameterized to reduce the burden of the model selection phase, unsatisfactory results are generally obtained. This inaccuracy problem can be somewhat circumvented by focus...