Anti-oxidant effects of propofol (2, 6-diisopropylphenol) were evaluated agains carbon tetrachloridet CCl4 -induced oxidative stress in rat liver. 30 male rats were equally divided in to 6 groups (5 rats each). Group I (control), while Group II was given CCl4 (3 mL /Kg/day, IP). Animals of Groups III received only propofol (10 mg/Kg/day, IP). Group IV was given propofol+ CCl4. Group V was admin...

the clinical uses of gentamicin have so far been restricted due to nephrotoxicity and ototoxicity. the exact mechanism of nephrotoxicity is still unknown; however, it appears that free radicals may be involved. methionine has previously been shown to alleviate oxidative stress involved in ototoxicity due to its antioxidant properties. therefore, the effect of methionine supplementation on the g...

a good knowledge of the parameters causing casing damage is critically important due to vital role of casing during the life of a well. cement sheath, which fills in the gap between the casing and wellbore wall, has a profound effect on the resistance of the casing against applied loads. most of the empirical equations proposed to estimate the collapse resistance of casing ignore the effects of...

conclusions with regard to the potent antioxidant properties of silymarin, the neuroprotective effects of this natural compound suggested in the current study may in part be mediated through inhibition of oxidative stress. results exposure to acr reduced cell viability in pc12 cells. pre-treatment of cells with silymarin (100 µm) significantly reduced acr-induced toxicity. in addition, administ...

Although several studies have investigated the effect of degradation on the behavior of structures, investigations on collapse margin ratios are rare in the literature. In this study, the effect of strength and stiffness degradation on collapse capacity of steel moment frames is investigated. The aim is to determine margin of safety against collapse using a probabilistic approach. For this reas...

progressive collapse is a chain reaction of failures propagating throughout a portion of the structure disproportionate to the original local failure occurring when a sudden loss of a critical load‐bearing element initiates a structural element failure, eventually resulting in partial or full collapse of the structure. both general services administration (gsa) and united states department of d...

Inducible nitric oxide synthase (iNOS) gene expresses a calcium calmudolin-independent enzyme which can catalyse NO production from L-arginine. The induction of iNOS activity has been demonstrated in a wide variety of cell types under stimulation with cytokines and lipopoly saccharide (LPS). Previous studies indicated that all nitric oxide synthases (NOS) activated in human umbilical vein endot...