Methods: Patients who were diagnosed as idiopathic SSNHL and received no therapy were included in the study. Patients were divided into control and study groups. Patients in the study group received concurrent intratympanic steroid treatment with systemic steroid therapy. Patients in the control group received standard systemic steroid treatment alone. The duration of time before the treatment ...

BACKGROUND AND AIMS A severe flare-up develops in approximately 15% of patients with ulcerative colitis (UC). It is questionable whether the response to the first parenteral corticosteroid therapy decreases the risk for colectomy. Our aim was to evaluate the association between long-term colectomy rate and the efficacy of steroids in the first few days of the therapy and to assess other predict...

Thirty-six ciclosporin-prednisone-treated recipients of nonmatched cadaver renal allografts were given a course of Orthoclone OKT3 monoclonal antibody for steroid-resistant cell-mediated rejection. Although side effects were common, only 2 patients had to be withdrawn from therapy and there were no deaths related to therapy. Twenty-three (63.9%) allografts were rescued with OKT3 therapy and 21 ...

background: low-level laser therapy (lllt) has shown a promising effect in ameliorating symptoms of rheumatoid arthritis (ra). the aim of this investigation was to compare the early and late antiinfl ammatory effects of lllt and betamethasone in ra. materials and methods: in this animal experimental study, after inducing a model of ra in temporomandibular joint (tmj) of 37 wistar rats using adj...

Etanercept, a TNF-α inhibitor, has been reported to be effective in SJS/TEN and is considered new treatment option. We conducted study evaluate the safety efficacy of etanercept patients who do not respond well steroid therapy. Four cases with no response for therapy (PSL 20 mg/day or more) enrolled this study. Etanercept was administered subcutaneously (50 mg) once week while continued. Althou...

One adverse effect of methylprednisolone (MP) pulse therapy is an acute dose-dependent increase in the blood glucose level. Five patients with thyroid ophthalmopathy but normal glucose tolerance received MP pulse therapy (3 cycles, 3 days/week) and were assessed by continuous glucose monitoring. Steroid therapy increased the mean sensor glucose level, and all patients developed steroid-induced ...

A 50-year-old woman was diagnosed with acute-onset autoimmune hepatitis. She did not respond to steroid therapy including pulse therapy, and was subsequently treated with living donor-liver transplantation 36 days after the beginning of steroid therapy. Except for a period of transient mild acute rejection, her liver function tests remained within a normal range for 2.5 years after the operatio...

Dismenore dibagi atas jenis primer (tanpa kondisi patologik pelvis) dan sekunder (dengan pelvis). Diagnosis dismenore berdasarkan anamnesis pemeriksaan fisik yang teliti. Penanganan di fasilitas kesehatan adalah diagnosis tata laksana menyingkirkan kecurigaan sekunder. Obat anti-inflamasi non-steroid (OAINS) terapi hormonal merupakan lini pertama untuk primer.
 Dysmenorrhea is categorized ...

In this multicenter, open-label, randomized controlled trial, we determined whether 2-month prednisolone therapy for steroid-sensitive nephrotic syndrome was inferior or not to 6-month therapy despite significantly less steroid exposure. The primary end point was time from start of initial treatment to start of frequently relapsing nephrotic syndrome. The pre-specified non-inferiority margin wa...

Background. High-dose inhaled steroid therapy has been shown to be effective in children and adults with asthma exacerbations. However, few reports are available regarding its efficacy for asthma exacerbations in younger children. Objective. In this study, we administered high-dose nebulized budesonide therapy for mild asthma exacerbations in children < 3 years of age and compared its efficacy ...