BACKGROUND Unresectable intrahepatic and hilar cholangiocarcinomas carry a dismal prognosis. Systemic chemotherapy and conventional external beam radiation and brachytherapy have been used with limited success. We explored the use of stereotactic body radiotherapy (SBRT) for these patients. METHODS Patients with unresectable intrahepatic or hilar cholangiocarcinoma or those with positive marg...

Nephron-sparing surgery is currently the standard of care for the management of small renal masses. While both neoadjuvant and adjuvant conventional external beam radiotherapy have failed to demonstrate an oncologic benefit for the treatment of renal cell carcinoma, more recent work aims to explore the utility of stereotactic radiotherapy. We present the case of a 70-year-old woman who failed ...

Superior vena cava syndrome (SVCS) is characterized by a spectrum of clinical findings that result from the occlusion of the superior vena cava (SVC), usually caused by extracaval compression of the SVC by either a bronchogenic tumor or an enlarged mediastinal lymph node. Most efforts at treatment for SVCS are palliative, and long-term survival for malignancy-related SVCS is very low. Therefore...

Objectives: To evaluate the feasibility, efficacy and toxicity of robotic stereotactic body radiotherapy for the treatment of unresectable hepatic oligometastases. Methods: Between 09/2010 and 06/2015, 43 consecutive patients (19 female, 24 male, median age at treatment: 69.8 ; range, 43-83 years) with up to three synchronous or metachronous hepatic oligometastases were referred for Cyberknife ...

BACKGROUND Recurrent nasopharyngeal carcinoma (NPC) after previous radiotherapy is challenging. There is no standard approach for salvage treatment. Here we present toxicity and treatment results for recurrent NFC patients who underwent fractionated stereotactic radiotherapy (FSRT) as second line radiotherapy (RT). MATERIALS AND METHODS Between April 2009 and July 2012, 24 patients, with a ma...

This white paper will focus on the definition, epidemiology, diagnosis, staging and treatment of head and neck cancers with sections I – VIII comprising a general view of head and neck cancer from the National Cancer Institute (more information can be found at www.cancer.gov). Sections IX and X (available to society members only) will provide a literature review on stereotactic body radiotherap...

STUDY DESIGN A broad narrative review. OBJECTIVES The objective of this article is to provide a technical review of spine stereotactic body radiotherapy (SBRT) planning and delivery, indications for treatment, outcomes, complications, and the challenges of response assessment. The surgical approach to spinal metastases is discussed with an overview of emerging minimally invasive techniques. ...

Stereotactic body radiation therapy (SBRT) is a newly developed technique currently in clinical use. SBRT originated from stereotactic radiosurgery for intracranial tumors. SBRT has been widely used clinically for lung cancer. The practice of SBRT demands different kinds of patient fixation, breathing control, target determination, treatment planning, and verifications. The history and current ...

More than 100,000 new cases of bone metastases are diagnosed each year, and they present an important clinical problem. They cause significant morbidity and quality-of-life issues in cancer patients. Conventional external-beam radiotherapy is currently the most common method to treat these metastases, with several randomized controlled trials showing no difference in effectiveness between multi...

OBJECTIVES After adjuvant or definitive radiation for pancreas cancer, there are limited conventional treatment options for recurrent pancreas cancer. We explored the role of (Stereotactic Body Radiotherapy) SBRT for reirradiation of recurrent pancreas Cancer. METHODS This is a retrospective study of patients reirradiated with SBRT for recurrent pancreas cancer. All patients were deemed unres...