AIM To compare two reference standards when evaluating a method of screening for referable diabetic retinopathy. METHOD Clinics at Oxford and Norwich Hospitals were used in a two centre prospective study of 239 people with diabetes receiving an ophthalmologist's examination using slit lamp biomicroscopy, seven field 35 mm stereophotography and two field mydriatic digital photography. Patients...

Word matches are often used in sequence comparison methods, either as a measure of sequence similarity or in the first search steps of algorithms such as BLAST or BLAT. The D2 statistic is the number of matches of words of k letters between two sequences. Recent advances have been made in the characterization of this statistic and in the approximation of its distribution. Here, these results ar...

We propose a new method of gravitational wave detection using a modified form of higher criticism, a statistical technique introduced by Donoho & Jin (2004). Higher criticism is designed to detect a group of sparse, weak sources, none of which are strong enough to be reliably estimated or detected individually. We apply higher criticism as a second-pass method to synthetic F-statistic and C-sta...

For the evaluation of results from remote sensing and high-resolution spatial models it is often necessary to assess the similarity of sets of maps. This paper describes a method to compare raster maps of categorical data. The method applies fuzzy set theory and involves both fuzziness of location and fuzziness of category. The fuzzy comparison yields a map, which specifies for each cell the de...