Abstract The efficacy and safety of Hydroxychloroquine (HCQ) in treating coronavirus disease (COVID-19) is disputed. This systematic review meta-analysis aimed to examine the HCQ addition standard care (SOC) COVID-19. PubMed, Cochrane Library, Embase, Web sciences, medRxiv were searched up March 15, 2021. Clinical studies registry databases also for identifying potential clinical trials. refere...