An iron-catalysed cascade synthesis of pyrroles from nitroarenes was developed. The homogeneous catalyst shows remarkable activity at room temperature. Its wide functional group tolerance enables late-stage functionalization drug(-like) molecules.

We consider a dynamic network cascade process developed by Watts [20] applied to a random networks with a specified amount of clustering, belonging to a class of random networks developed by Newman [19]. We adapt tree-based methods from [20] to formulate an appropriate two-type branching process to describe the spread of a cascade started with a single active node, and obtain a fixed-point equa...

A nonlinear L2-gain property that generalizes the conventional (linear) notion of L2-gain for finite dimensional dynamical systems is studied. In particular, an optimizationbased approximation strategy that facilitates computation of gain bounds via a cascade is presented. The cascade in question consists of the dynamical system under test, driven by a nonlinear “energy saturation” operator tha...

Polystyrene(40)-b-poly(isocyanoalanine(2-thiophen-3-yl-ethyl)amide)(50) (PS-PIAT) polymersomes have the unique property of being sufficiently porous to allow diffusion of small (organic) substrates while retaining large biomolecules such as enzymes inside. Herein we report on the encapsulation and protection of glucose oxidase (GOx) and horse radish peroxidase (HRP) in PS-PIAT polymersomes and ...

Viola et al. have introduced a rapid object detection framework based on a boosted cascade of simple feature classifiers. In this paper we extend their work and achieve two contributions. Firstly, we propose a novel feature definition and introduce a feature shape mask to represent it. The defined features are scale-invariant which means the features can be rescaled easily and reduce the perfor...

Heterologous expressions and purifications of all WelU proteins from the welwitindolinone pathways in Hapalosiphon welwitschii UTEX B1830 and IC-52-3 led to the discovery that WelU1 and WelU3 selectively assemble 12-epi-fischerindole U (2) and 12-epi-hapalindole C (1), respectively, from 3-geranyl 3-isocyanovinyl indolenine (4) via an enzymatic cascade featuring the Cope rearrangement, stereose...