Preceding NMR experiments show that the conformation of tandem GA base pairs, an important recurrent non-canonical building block in RNA duplexes, is context dependent. The GA base pairs adopt "sheared" N3(G)-N6(A), N2(G)-N7(A) geometry in the r(CGAG)(2) and r(iGGAiC)(2) contexts while switching to "imino" N1(G)-N1(A), O6(G)-N6(A) geometry in the r(GGAC)(2) and r(iCGAiG)(2) contexts (iC and iG ...

We explore a stacked framework for learning to predict dependency structures for natural language sentences. A typical approach in graph-based dependency parsing has been to assume a factorized model, where local features are used but a global function is optimized (McDonald et al., 2005b). Recently Nivre and McDonald (2008) used the output of one dependency parser to provide features for anoth...

A novel wideband RF system, nicknamed the barrier RF, has been designed, fabricated and installed in the Fermilab Main Injector. The cavity is made of seven Finemet cores, and the modulator made of two bipolar high-voltage fast solid-state switches. The system can deliver ±7 kV square pulses at 90 kHz. The main application is to stack two proton batches injected from the Booster and squeeze the...

Ensemble methods, such as stacking, are designed to boost predictive accuracy by blending the predictions of multiple machine learning models. Recent work has shown that the use of meta-features, additional inputs describing each example in a dataset, can boost the performance of ensemble methods, but the greatest reported gains have come from nonlinear procedures requiring significant tuning a...

Standard stacking procedures are based on the combination of many scalar traces, and can exploit the coherency of arrivals between traces using non-linear methods. Such stacks can be used with some success for three-component data but do not exploit the vector character of the seismic wave¢eld. A set of stacking methods are introduced to work directly with three-component data and include inter...

The use of appropriate level of theories for studying weak interactions such as 8-8 stackinginteractions of aromatic molecules has been an important aspect, since the high level methods havelimitations for application to large molecules. The differences in the stacking energies of variousaromatic molecular structures are found significant. It is also very important for identifying the mostfavor...

BACKGROUND Manual and mechanical cough-augmentation techniques can improve peak cough flow (PCF) in patients with respiratory insufficiency caused by neuromuscular disease. METHODS We studied cough-augmentation techniques in 179 clinically stable patients with various neuromuscular diseases. We measured vital capacity (VC), maximum expiratory pressure (MEP), and PCF, with and without 3 cough-...

A chiral Lewis acid catalysed asymmetric [2+2] cycloaddition reaction of allenyl imide and alkenes was developed by Xiaohua Liu, Xiaoming Feng et al. in their Research Article (e202211596). This protocol provided a series axially cyclobutenes high yields with excellent enantioselectivities. stepwise mechanism proposed based on experimental studies DFT calculations, π–π stacking interactions wer...

By taking into account base-base stacking interactions we improve the Generalized Model of Polypeptide Chain (GMPC). Based on a one-dimensional Potts-like model with many-particle interactions, the GMPC describes the helix-coil transition in both polypeptides and polynucleotides. In the framework of the GMPC we show that correctly introduced nearest-neighbor stacking interactions against the ba...