نتایج جستجو برای: sry

تعداد نتایج: 1626  

Journal: :Development 1993
R Jiménez M Burgos A Sánchez A H Sinclair F J Alarcón J J Marín E Ortega R Díaz de la Guardia

We investigated the origin of XX sex reversal in the insectivorous mole Talpa occidentalis. Cytogenetic, histological and hormonal studies indicate that all XX individuals analyzed from two different populations are true hermaphrodites, with ovotestes. This suggests that XX sex reversal may be the norm in this species. The intersexes are functional fertile females and the trait is transmitted a...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - دانشکده کشاورزی 1389

در این مطالعه به منظور امکان سنجی تعیین جنسیت اسپرم گاو توسط تکنیک real-time pcr،تعداد کپی ژنsry که مسئول تولید صفات ثانویه جنسی درجنس نر و بر روی کروموزوم yقراردارد به عنوان شاخص برای شمارش تعداد کروموزوم yدر اسپرم وتعداد کپی ژن plp که مسئول تولید پروتئولیپید پروتئین و بر روی کروموزوم x می باشد، به عنوان شاخص برای شمارش تعداد کروموزوم x در اسپرم در نظر گرفته شدند. بدین منظور استخراج dnaبا یک ر...

2014
Tian-Fu Li Qiu-Yue Wu Cui Zhang Wei-Wei Li Qing Zhou Wei-Jun Jiang Ying-Xia Cui Xin-Yi Xia Yi-Chao Shi

BACKGROUND 46,XX testicular disorder of sex development is a rare genetic syndrome, characterized by a complete or partial mismatch between genetic sex and phenotypic sex, which results in infertility because of the absence of the azoospermia factor region in the long arm of Y chromosome. CASE PRESENTATION We report a case of a 14-year-old male with microorchidism and mild bilateral gynecomas...

2013
Liuliu Zheng Leonardo A. Sepúlveda Rhonald C. Lua Olivier Lichtarge Ido Golding Anna Marie Sokac

Robustness is a property built into biological systems to ensure stereotypical outcomes despite fluctuating inputs from gene dosage, biochemical noise, and the environment. During development, robustness safeguards embryos against structural and functional defects. Yet, our understanding of how robustness is achieved in embryos is limited. While much attention has been paid to the role of gene ...

Journal: :The International Journal of Biochemistry & Cell Biology 2008

Journal: :Molecular Endocrinology 2008

2011
VeRnOn A. ROSARIO Vernon A. Rosario

R. JOneS was surprisingly relaxed and jovial considering that he had driven two hours from Bakersfield to Los Angeles to have his thirteen-month-old child examined by half a dozen doctors. no doubt he was sustained by his faith: on his T-shirt was boldly emblazoned “Got Jesus?” The examination rooms are usually crowded in the Intersex Clinic (now the Disorders of Sex Development [DSD] Clinic) a...

2015
XIN-YI XIA CUI ZHANG TIAN-FU LI QIU-YUE WU NA LI WEI-WEI LI YING-XIA CUI XIAO-JUN LI YI-CHAO SHI

The 46,XX male disorder of sex development (DSD) is rarely observed in humans. Patients with DSD are all male with testicular tissue differentiation. The mechanism of sex determination and differentiation remains to be elucidated. In the present case report, an 46,XX inv (9) infertile male negative for the sex‑determining region of the Y chromosome (SRY) gene was examined. This infertile male w...

2015
Yuria UMEMURA Ryosuke MIYAMOTO Rie HASHIMOTO Kyoko KINOSHITA Takuya OMOTEHARA Daichi NAGAHARA Tetsushi HIRANO Naoto KUBOTA Kiichi MINAMI Shogo YANAI Natsumi MASUDA Hideto YUASA Youhei MANTANI Eiko MATSUO Toshifumi YOKOYAMA Hiroshi KITAGAWA Nobuhiko HOSHI

Mammalian sexual fate is determined by the presence or absence of sex determining region of the Y chromosome (Sry) in the "bipotential" gonads. Recent studies have demonstrated that both male and female sexual development are induced by distinct and active genetic pathways. Breeding the Y chromosome from Mus m. domesticus poschiavinus (POS) strains into C57BL/6J (B6J) mice (B6J-XY(POS)) has bee...

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