The diagnostic value of circulating SEPT9 DNA methylation in patients with colorectal cancer remains controversial. Thus, we performed a systematic review and meta-analysis to assess diagnostic accuracy of SEPT9 DNA methylation for colorectal cancer (CRC). We conducted a comprehensive literature search in PubMed, the Cochrane library, Web of Science databases and Chinese National Knowledge Infr...

Despite the advancement of neuroimaging techniques, it often remains a diagnostic challenge to distinguish recurrent glioma from lesions representing treatment effect. Preliminary reports suggest that 11C-methionine Positron emission tomography (PET) can assist in diagnosing true glioma recurrence. We present here a meta-analysis to assess the accuracy of 11C-methionine PET in identifying recur...

AUC is an important performance measure and many algorithms have been devoted to AUC optimization, mostly by minimizing a surrogate convex loss on a training data set. In this work, we focus on one-pass AUC optimization that requires going through the training data only once without storing the entire training dataset, where conventional online learning algorithms cannot be applied directly bec...

As a common antagonist of Wnt/β-catenin signaling, Wnt inhibitory factor 1 (WIF1) plays an important role in the tumor progression. The aim of our meta-analysis was to summarize the diagnostic value of WIF1 methylation in colorectal cancer (CRC). Eligible studies were retrieved by a systemic search among PubMed, Embase, CNKI, and Wanfang literature databases. The diagnostic value of WIF1 methyl...

BACKGROUND The instantaneous wave-free ratio (iFR) is a new vasodilator-free index of coronary stenosis severity. The aim of this meta-analysis is to assess the diagnostic performance of iFR for the evaluation of coronary stenosis severity with fractional flow reserve as standard reference. METHODS We searched PubMed, EMBASE, CENTRAL, ProQuest, Web of Science, and International Clinical Trial...

BACKGROUND As an evolving imaging modality, PET/MRI is preliminarily applied in clinical practice. The aim of this study was to assess the diagnostic performance of PET/MRI for tumor staging in patients with various types of cancer. METHODS Relevant articles about PET/MRI for cancer staging were systematically searched in PubMed, EMBASE, EBSCO and the Cochrane Library. Two researchers indepen...

OBJECTIVE We aimed to do a meta-analysis of the existing literature to assess the accuracy of prostate cancer studies which use magnetic resonance spectroscopy (MRS) as a diagnostic tool. MATERIALS AND METHODS Prospectively, independent, blind studies were selected from the Cochrane library, Pubmed, and other network databases. The criteria for inclusion and exclusion in this study referenced...

Christopher A. Duplessis, Marvin J. Sklar, Ryan C. Maves, Anne Spichler, Braden Hale, Mark Johnson, Mary Bavaro, and Joseph M. Vinetz Author affi liations: Naval Medical Center, San Diego, California, USA (C.A. Duplessis, M.J. Sklar, R.C. Maves, M. Johnson, M. Bavaro); University of California, La Jolla, California, USA (A. Spichler, J.M. Vinetz); and Naval Health Research Center, San Diego (B....