Some animals routinely endure serious injuries from predators or during intraspecific territorial conflicts. Such is the case for Amphiuma tridactylum, an aquatic salamander that lives in an environment rich in potentially infectious microbes, apparently with rare or no pathogenic infection. Some vertebrates possess innate immune mechanisms, but whether this is the case for Amphiuma is unknown....

The organs, tissues, and cells of the lymphoreticular system have received considerable attention as targets for chemicals causing adverse effects. A basic toxicological approach is described for assessing the risk of a chemical perturbing the immune system. CD-1 mice were exposed for 14 or 90 days to one of several chlorinated hydrocarbons: 1,2-dichloroethane, 1,2-dichloroethylene or 1,1,2-tri...

The in vivo effects of fructus Schizandrae and radix Eleutherococci combined extracts on various parameters of lymphocyte activity in Balb/c mice were studied. Feeding mice 300, 600 or 1200 μg of the extracts per day for 7 d, produced the activation of chemokinetic activity of spleen lymphocytes, enhancement of proliferative response of splenocytes and blood lymphocytes to mitogens, stimulation...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 185 No. 5 917–928 www.jcb.org/cgi/doi/10.1083/jcb.200903020 JCB 917 Correspondence to Sergio Grinstein: [email protected] Abbreviations used in this paper: FRET, fluorescence resonance energy transfer; LUV, large unilamellar vesicle; mRFP, monomeric RFP; PA, phosphatidic acid; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PI, pho...

turnips with a long history of usage, are helpful in preventing breast and prostate cancer, inflammation and body`s immune system dysfunction. in this study, we investigated the effects of chloroform, ethyl acetate and methanolic extracts of brassica rapa l. on cell-mediated immune response in mice. chloroform, ethyl acetate and methanolic extracts of b. rapa glands were prepared by maceration ...