laboratory-scale experiments were conducted to evaluate the joint action toxicity and biochemicaleffects of sublethal concentrations of forcados light crude oil (flco) and three dispersants against clariasgariepinus over a period of 28 days. the derived 96hrlc50 values revealed that the dispersant, ds/tt/066(0.03ml/l) was the most toxic, followed by dispersant, oc/tt/osi (0.19ml/l), flco (5.06m...

Pre‐mRNA splicing requires the activities of small nuclear ribonucleoproteins and other essential splicing factors. Among these are members of the SR protein family and SR‐related proteins, which are integrally involved in regulating exon recognition, spliceosomal assembly, and spliceosomal re‐arrangements to promote intron excision. This chapter will focus on the discovery of SR proteins and S...

This paper introduces the concept of safety-related (SR) uncertainty and the methodology to measure SR uncertainty. SR uncertainty is concerned with the effect of parameter uncertainty on the uncertainty of system unsafety (defined with respect to achieved safety integrity level), which is in direct contrast to the effect on overall system uncertainty. The properties of SR uncertainty are discu...

The Sex-Ratio (SR) phenomenon is associated with the X chromosome of many species of Drosophila. Males carrying SR transmit predominantly sperm bearing the X chromosome. SR, therefore, has a very significant advantage in segregation. This paper provides an experimental analysis of the role of virility selection in preventing the fixation of SR. SR males are found to suffer substantial virility ...

This note gives a simple analysis of the randomized approximation scheme for matrix multiplication of Drineas et al. (2006) with a particular sampling distribution over outer products. The result follows from a matrix version of Bernstein’s inequality. To approximate the matrix product AB⊤ to spectral norm error ε‖A‖‖B‖, it suffices to sample on the order of (sr(A) ∨ sr(B)) log(sr(A) ∧ sr(B))/ε...

The decay of the very neutron-rich nucleus 100 Rb has been studied by γ-spectroscopy of on-line mass-separated samples. Schemes for β-decay to 100 Sr and βn-decay to 99 Sr are presented. New sets of transitions in 99 Sr and 100 Sr with identical energies are observed. All identical bands so far observed in neutron-rich Sr isotopes obey a simple energy rule valid for even-even, odd-even and odd-...

Scavenger receptor class B type I (SR-BI) is an HDL receptor that promotes bidirectional fl ux of free cholesterol between cells and HDL, as well as selective uptake of HDL cholesteryl ester into hepatocytes and steroidogenic cells ( 1, 2 ). Single deletion of mouse SR-BI accelerates atherosclerosis, whereas combined deletion of SR-BI and ApoE mimics several features of human coronary disease, ...

The objective of research was to explore the suitability of lipids like compritol 888 ATO and stearic acid as release retardant to develop sustained release (SR) tablets. The SR micromatrices of lipid (s) and glipizide were prepared (LM1- LM6) as intermediate product by fusion method and assessed for various pharmacotechnical properties. Micromatrices were formulated as SR tablets (F1-F6) by di...

Previous ventricular myocyte studies indicated that ryanodine receptors (RyRs) are in the sarcoplasmic reticulum (SR) and are critical in excitation-contraction coupling, whereas the inositol trisphosphate (InsP(3)) receptors are separately localized on the nuclear envelope (NucEn) and involved in nuclear Ca(2+) signaling. Here, we find that both caffeine and InsP(3) receptor agonists deplete f...

Previous ventricular myocyte studies indicated that ryanodine receptors (RyRs) are in the sarcoplasmic reticulum (SR) and are critical in excitation–contraction coupling, whereas the inositol trisphosphate (InsP3) receptors are separately localized on the nuclear envelope (NucEn) and involved in nuclear Ca signaling. Here, we find that both caffeine and InsP3 receptor agonists deplete free [Ca ...