Eukaryotic peroxiredoxins are highly susceptible to sulfinic acid formation. This overoxidation, which is thought to convert peroxiredoxins into chaperones, can be reversed by sulfiredoxins. Several organisms, including Caenorhabditis elegans, lack sulfiredoxins but encode sestrins, proteins proposed to be functionally equivalent. We induced peroxiredoxin overoxidation in C. elegans with a shor...

Forouzesh and colleagues recently reported an increase in vancomycin ototoxicity in parallel with the increasing use of higher vancomycin doses (4). The report suggests an overall incidence of vancomycin-induced ototoxicity of 12%, doubling historic estimates (3). This is a surprisingly high estimate for a drug that many experts do not consider to be ototoxic (5, 6). The authors have outlined s...

Volume 4, Issue 1, January – February 2015 Page 11 Abstract More information is transmitted in a digital format now than ever. Digital watermarking technology is a method of protecting copyrights for this information. In this paper, new watermarked algorithm is suggested. This algorithm consists of three stages, the first one, image is divided into several blocks, and these blocks are tested to...

Epidemiologic studies of the effects of religion on blood pressure suggest that religious commitment is inversely associated with blood pressure and that several religious denominations or groups have relatively low rates of hypertension-related morbidity and mortality. In this review, we examine the implication that certain characteristics and functions of religion account for this association...

The spectrum of calcific aortic valve disease ranges from aortic sclerosis, without obstruction to ventricular outflow, to severe aortic stenosis. The natural history of symptomatic and asymptomatic severe aortic valve stenosis has been evaluated by Doppler echocardiography in several retrospective and prospective studies. In addition, there is substantial data on the rate of haemodynamic progr...

traumatic brain injury (tbi) is one of the major causes of severe disability and death in the entire world that accidents are mentioned as main factors of it. tbi lead to primary and secondary injuries.  primary injuries are created immediately after accidents or bleeding but the secondary injuries are created by complicated process of cellular and molecular responses following primary injury a...