GPRC5A functions as a lung tumour suppressor to prevent spontaneous and environmentally induced lung carcinogenesis; however, the underlying mechanism remains unclear. Here we reveal that GPRC5A at the endoplasmic reticulum (ER) membrane suppresses synthesis of the secreted or membrane-bound proteins including a number of oncogenes, the most important one being Egfr. The ER-located GPRC5A distu...

Despite being forbidden in equilibrium, spontaneous breaking of time translation symmetry can occur in periodically driven, Floquet systems with discrete time-translation symmetry. The period of the resulting discrete time crystal is quantized to an integer multiple of the drive period, arising from a combination of collective synchronization and many body localization. Here, we consider a simp...

Verbmobil is a large German joint research project in the area spontaneous speech-to-speech translation sytems which is sponsored by the German Federal Ministery for Research and Education. In its first phase (1992–1996) ca. 30 research groups in universities, research institutes and industry were involved, and it entered its second phase in January 1997. The overall goal is develop a system wh...

Text segmentation task is an essential processing task for many of Natural Language Processing (NLP) such as text summarization, text translation, dialogue language understanding, among others. Turns segmentation considered the key player in dialogue understanding task for building automatic HumanComputer systems. In this paper, we introduce a novel approach to turn segmentation into utterances...

Birt-Hogg-Dubé (BHD) syndrome is a rare autosomal dominant disorder that affects the skin, kidney, and lungs. Affected individuals have an increased risk of developing multiple cysts in the lungs and a spontaneous pneumothorax. Germline mutations in the folliculin (FLCN) gene have been confirmed as the aetiology of BHD syndrome. A 51-year-old Indonesian female presented with recurrent spontaneo...

In this paper, we investigate the task of translating spontaneous speech transcriptions by employing aligned movie subtitles in training a statistical machine translator (SMT). In contrast to the lexical-based dynamic time warping (DTW) approaches to bilingual subtitle alignment, we align subtitle documents using time-stamps. We show that subtitle time-stamps in two languages are often approxim...

in the west, translation studies as a discipline has a very short but lively history. founded in the early 1970s in the low countries—holland and belgium—translation studies is a fairly new field. yet, today some theorists suggest that the discipline is too limited to translated texts and excludes much translation data being generated from other fields of inquiry, including theater, art, archit...

no doubt that the simultaneous interpretation is one of the most difficult types of translation. this type of translation, which is sometimes called oral translation, has many challenges that are familiar to and tangible for the translators. these challenges can be examined in two grounds; first, the content and mechanism of translation, and second, the translator himself. although translators ...

Expression of the tet resistance gene from plasmid pBC16 is induced by the antibiotic tetracycline, and induction is independent of the native promoter for the gene. The nucleotide sequence at the 5' end of the tet mRNA (the leader region) is predicted to assume a complex secondary structure that sequesters the ribosome binding site for the tet gene. A spontaneous, constitutively expressed tet ...

The mathematical structure of the temporal gauge of QED is critically examined in both the alternative formulations characterized by either positivity or regularity of the Weyl algebra. The conflict between time translation invariance and Gauss law constraint is shown to lead to peculiar features. In the positive case only the correlations of exponentials of fields exist (non regularity), the s...