OBJECTIVE To determine the frequency, clinical features, and radiological and bone scintigraphic changes of spondylodiscitis in patients with SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis). METHODS The study was retrospective. Data from patients with the diagnostic criteria of SAPHO syndrome were analysed for clinical features, biological data (HLA B antigen), and pelvic and ...

Spine involvement is less common in Reiter's syndrome than in other seronegative spondyloarthropathies. Also, cervical spine involvement rarely occurs in Reiter's syndrome and other spondyloarthropathies. This paper reports a rare case of Reiter's syndrome in which there was cervical spine involvement that presented clinically as an atlanto-axial rotatory subluxation. Reiter's Syndrome (RS) is ...

Over the last ten years, the treatment of seronegative spondyloarthropathies has changed dramatically with the introduction of the anti-tumor necrosis factor alpha (TNFα) agents. Nevertheless, there is a growing number of studies describing several adverse reactions in patients treated with biological agents. In the present report we describe the case of a 22-year-old male patient with ankylosi...

Spondyloarthropathies (SpA) are characterised by dysregulation of the inflammatory processes and bone metabolism which may be clarified by gene expression profiles. Sharma and colleagues showed associations of axial SpA with the innate immune system, inflammation markers and markers of bone remodeling. Drawbacks of this study are the patient selection based on uveitis, which limits the extrapol...

We reviewed the case notes and X-rays of all patients with knee arthritis treated with yttrium-90 for the first time at a single institution from November 1981 to November 1995. Outcomes were assessed as 'improved' or 'not improved' by review of the case notes at 3, 6 and 12 months, and by the absence of further intra-articular (IA) steroid injections. Of the 121 knees treated, 87 had adequate ...

OBJECTIVES Early diagnosis of rheumatoid arthritis (RA) is an unmet medical need in the field of rheumatology. Previously, we performed high-density transcriptomic studies on synovial biopsies from patients with arthritis, and found that synovial gene expression profiles were significantly different according to the underlying disorder. Here, we wanted to further explore the consistency of the ...

ankylosing spondylitis and related spondyloarthropathies. Rheum Dis Clin North Am 1995;21:117–28. 2. D’Agostino MA, Breban M, Said-Nahal R, Dougados M. Refractory inflammatory heel pain in spondylarthropathy: a significant response to infliximab documented by ultrasound. Arthritis Rheum 2002;46:840–1. 3. Olivieri I, Padula A, Barozzi L. The enthesiopathy: clinical manifestations, imaging and tr...

Reiter's syndrome is a condition of unknown aetiology, generally thought to be of infective origin. It occurs mainly in young men and is characterized by urethritis, arthritis, and conjunctivitis. Less common findings include ankylosing spondylitis, iritis, balanitis, keratoderma blennorrhagica and other skin lesions, stomatitis, and inflammations of the tendons and fasciae. According to the li...

F. 1.—Decrease of erythrocyte sedimentation rate (dESR) according to Westergren (mm in first and second hour), C-reactive protein (dCRP) (in mg/l) and rheumatoid factor (dRF) (IU/ml) during the follow-up period (=pre-therapeutic level minus 6 month level) shown in percentage points. 4. Guaydier-Souquieres C, Beguin J, Ollivier D, Loyau G. Knee arthroscopy after yttrium or osmic acid injection...

Haglund's syndrome, which is an inflammation of the bursa and a bony enlargement on the back of the heel that most often leads to painful bursitis, is a rare cause of retrocalcaneal pain. The clinical diagnosis is often confusing as the clinical picture may mimic other causes of hindfoot pain such as isolated retrocalcaneal bursitis or hindfoot involvement from more systemic disorders such as s...