Protective autoimmunity (PA) is a physiological response to central nervous system trauma that has demonstrated to promote neuroprotection after spinal cord injury (SCI). To reach its beneficial effect, PA should be boosted by immunizing with neural constituents or neural-derived peptides such as A91. Immunizing with A91 has shown to promote neuroprotection after SCI and its use has proven to b...

how to cite this article: abbad a, afzal k, mujeeb aa, shahab t, khalid m. spontaneous ventral spinal epidural hematoma in an infant: an unusual presentation. iran j child neurol. 2013  spring;7(2):47-50. abstract spontaneous ventral spinal epidural hematomas are extremely rare in children and clinically recognized by the appearance of acute asymmetric focal motor and sensory involvement. in in...

Copyright: © 2013 Ruppert LM. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Metastatic epidural spinal cord compression is the third most common cause of adult compressive myelopathy, after acute trauma and ...

Key highlights: Tabular columns organized by anatomical abnormality include imaging findings and a summary of key clinical data that correlates to the images Congenital/developmental abnormalities, spinal deformities, and acquired pathologies in both children and adults Lesions organized by region including dural, intradural extramedullary, extra-dural, and sacrum More than 600 figures illustra...

S pinal immobilization of all trauma patients with a cervical spine or spinal cord injury or with a mechanism of injury having the potential to cause cervical spinal injury is recommended. • Triage of patients with potential spinal injury at the scene by trained and experienced emergency medical services personnel to determine the need for immobilization during transport is recommended. • Immob...

Research studies on the three-dimensional (3D) morphological alterations of the spinal cord microvasculature after injury provide insight into the pathology of spinal cord injury (SCI). Knowledge in this field has been hampered in the past by imaging technologies that provided only two-dimensional (2D) information on the vascular reactions to trauma. The aim of our study is to investigate the 3...

The cell neural adhesion molecule contactin-2 plays a key role in axon extension and guidance, fasciculation, and myelination during development. We thus asked, whether contactin-2 is also important in nervous system regeneration after trauma. In this study, we used an adult zebrafish spinal cord transection model to test the functions of contactin-2 in spinal cord regeneration. The expression ...

Key highlights: Tabular columns organized by anatomical abnormality include imaging findings and a summary of key clinical data that correlates to the images Congenital/developmental abnormalities, spinal deformities, and acquired pathologies in both children and adults Lesions organized by region including dural, intradural extramedullary, extra-dural, and sacrum More than 600 figures illustra...

Key highlights: Tabular columns organized by anatomical abnormality include imaging findings and a summary of key clinical data that correlates to the images Congenital/developmental abnormalities, spinal deformities, and acquired pathologies in both children and adults Lesions organized by region including dural, intradural extramedullary, extra-dural, and sacrum More than 600 figures illustra...

Key highlights: Tabular columns organized by anatomical abnormality include imaging findings and a summary of key clinical data that correlates to the images Congenital/developmental abnormalities, spinal deformities, and acquired pathologies in both children and adults Lesions organized by region including dural, intradural extramedullary, extra-dural, and sacrum More than 600 figures illustra...