A total of 11 patients with combined traumatic injuries of the brachial plexus and spinal cord were reviewed retrospectively. Brachial plexus paralysis in such dual injuries tends to be diagnosed and treated late and the prognosis is usually poor. The associated injuries, which were all on the same side as the plexus lesion, were to the head (nine cases), shoulder girdle (five), thorax (nine) a...

The aim of this study was to describe the pattern of spinal cord injuries, MRI signal patterns and neurological impairment among spinal cord injury patients in Lagos, Nigeria. A retrospective study of the hospital records and MRI reports of 90 spinal cord injury patients at the Lagos University Teaching Hospital was conducted. The study included patients who presented at the hospital with spina...

As of mid 2001, out of the 34000 spinal injuries that took place in the previous year, over half (55%) were cervical spine injuries [18]. Additionally, out of all the cervical spinal injuries incurred by patients in the United States every year, 15% of those injuries are fatal [7]. Motor vehicle crashes are the leading cause of death for persons under 45 years of age, and the number one cause o...

We induced percutaneous spinal cord injuries (SCI) using a balloon catheter in 45 rats and transplanted human umbilical cord blood derived mesenchymal stem cells (hUCB-MSCs) at the injury site. Locomotor function was significantly improved in hUCB-MSCs transplanted groups. Quantitative ELISA of extract from entire injured spinal cord showed increased expression of brain-derived neurotrophic fac...

A major problem for neuroscientists and clinicians is why the central nervous system shows ineffective regeneration after injury. Injured peripheral nerve fibers reform their connections, whereas those in injured spinal cord never re-grow. Insights into the mechanisms for repair and restoration of function after spinal cord injury have been obtained by experiments showing that injured nerve cel...

A major problem for neuroscientists and clinicians is why the central nervous system shows ineffective regeneration after injury. Injured peripheral nerve fibers reform their connections, whereas those in injured spinal cord never re-grow. Insights into the mechanisms for repair and restoration of function after spinal cord injury have been obtained by experiments showing that injured nerve cel...

What are the most common causes of spinal cord contusion? Most spinal cord contusion injuries are the result of highimpact motor vehicle accidents. However, athletes can sustain this injury as a result of contact while playing. Fortunately, the number of serious incidents involving spinal cord injury is low. That being said, more orthopedists are beginning to function as the team physician duri...

Spinal cord injuries are commonly studied by causing injury to in vivo rodent spinal cords and analyzing histological and behavioral results post injury. However, very few researchers have investigated the dynamic behavior of the in vivo spinal cord during impact. This information would help to define relationships between impact parameters, internal structure deformation (such as grey and whit...

OBJECTIVES To assess the prevalence of carbohydrate and lipid disorders in adults with chronic spinal cord injury and evaluate their risk contribution to cardiovascular diseases and the potential impact of exercise and pharmacologic and dietary therapies to alter these disorders and reduce cardiovascular disease risk. DATA SOURCES MEDLINE (PubMed), Cochrane Database and Web sites of the Ameri...

There are extensive evidences that show axonal processes of the nervous system (peripheral and/or central) may be degenerated after nerve injuries. Wallerian degeneration and chromatolysis are the most conspicuous phenomena that occur in response to injuries. In this research, the effects of post-operative time following sciatic nerve crush on the number of spinal motoneurons were investigated....