Total lipid extracts from washed trypsinized human platelets were fractionated into neutral lipids, glycosphingolipids, and phospholipids by silicic acid chromatography. The concentrations and chemical structures of the neutral and acidic glycosphingolipids were then studied in detail. On the basis of sugar molar ratios, studies of permethylation products, and the action of stereospecific glyco...

A new fatty acid synthase off-loading domain. Fatty (FAS) usually releases its products by hydrolysis or transesterification. Here, an α-oxoamine domain is identified in a cyanobacterial type I FAS. This the acyl chain through condensation with L-serine, offering novel pathway to α-amino ketones that share similarities sphingolipid precursors. More information can be found Research Article A. E...