BACKGROUND AND OBJECTIVES Autoantibodies are immunglobulins occurred directly against autoantigens that are known as endogen antigens. Autoimmune disease is an occasion that the body begins a fight against its own cells and tissues. The antibodies that are created by the body against its own cell nuclei are called as anti-nuclear antibodies (ANA), and one of the methods used for detection and p...

Rowell Syndrome is a rare presentation of lupus erythematosus manifesting as an eruption erythema multiforme-like papules and plaques with immunological findings positive rheumatoid factor, speckled antinuclear antibodies, and/or anti-Ro/La antibodies. This case highlights the unusual highly debated in 66-year-old woman newly-appearing erythematous, targetoid setting previously diagnosed system...

CASE—PART I A previously healthy 38-year-old man with no history of cardiovascular disease presented with symptoms of upper respiratory tract infection, acute chest pain, inferior ST-elevation on ECG and a troponin I >60 μg/L (normal <0.04 μg/L). Emergency coronary angiography demonstrated normal coronary arteries. Echocardiogram showed moderate impairment of LV systolic function, inferoposteri...

Abstract Introduction Antinuclear antibodies (ANAs) are regarded as a hallmark of connective tissue diseases (CTDs) and play key role in their diagnosis, but the value some particular management patients disease prognosis is controversial. The mechanism underlying production ANAs CTDs, other chronic inflammatory conditions even healthy people, not completely elucidated. Anti‐DFS70 connected wit...