We show how to determine the k-th bit of Chaitin’s algorithmically random real number, Ω, by solving k instances of the halting problem. From this we then reduce the problem of determining the k-th bit of Ω to determining whether a certain Diophantine equation with two parameters, k and N , has solutions for an odd or an even number of values of N . We also demonstrate two further examples of Ω...

1. The reaction of glutamate dehydrogenase with N-acetylimidazole and with tetranitromethane leads to modification of tyrosine residues. 2. Modification of 1 tyrosine residue/subunit does not affect the enzymic activity but decreases the response of the enzyme to the allosteric inhibitor, GTP. 3. The physical properties of the enzyme (sedimentation coefficient and optical rotatory dispersion) r...

The single, uncross-linked polypeptide chain of the zymogen of the streptococcal proteinase is unfolded to a random structure in 6 M guanidinium chloride. When the denaturing agent is removed by dialysis, the potential enzymatic activity after tryptic hydrolysis and reduction is recoverable in 90% yield. Data on the unfolding process have been obtained by enzymatic assays and by optical rotator...

This paper examines crime hot spots near licensed premises in the night-time economy (NTE) to investigate whether hot spots of four different classification of crime and disorder co-occur in time and place, namely violence, disorder, drugs and criminal damage. It introduces the concept of multi-classification crime (MCC) hot spots; the presence of hot spots of more than one crime classification...

Time dependent density functional theory (TDDFT) and the conductor-like screening model (COSMO) of solvation were used to model the specific rotation and optical rotatory dispersion (ORD) of alanine, proline and serine solutions. Zwitterionic, cationic and anionic forms of amino acids were investigated and the results compared with experimental literature data obtained in neutral, acidic and ba...

A case has been presented in this paper for the use of spatial statistical techniques in analyzing crash data to investigate spatial patterns and spatial autocorrelation. “Weather-related” crashes in Wisconsin, aggregated on a county level, have been analyzed using spatial statistical techniques. The Getis-Ord Gi * statistic was used to identify spatial patters of different types of weather-rel...

W A SH IN G TO N (A P ) C on­ g ress re su m es its d ispu tes with P res id en t F ord th is week over U.S. covert aid to Angola and also on federa l spending. T h e H ouse p la n s to v o te T u e sd a y on a S e n a te -a p p ro v e d b an on th e A ngo la a id , tw o d a y s b e fo re a S e n a te F o re ig n R e la t io n s s u b c o m m itte e o p en s p u b lic h e a r in g s on U .S . p...

The rapid loss of ATPase activity of myosin from the red, or slow, skeletal muscles of the rabbit under mild alkaline conditions has been studied in detail. The loss of ATPase activity is irreversible and consistent with a mechanism involving two !irst order reactions with rate constants of 0.3 and 0.007 min-l. No gross change in molecular structure accompanies inactivation, as judged by the la...

We have reported in a previous paper (1) that optical rotatory dispersion measurements indicate that the native conformation of P-lactoglobulin, in aqueous solution, contains few, if any, regions with an a-helical structure. It appears likely, from the many studies of Jirgensons (2) that this conclusion is applicable to a large number of globular proteins, and we have suggested that this indica...