Chronic inflammation is a major risk factor for cancer, including gastric cancers and other gastrointestinal cancers. For example, chronic inflammation caused by autoimmune gastritis (AIG) is associated with an increased risk of gastric polyps, gastric carcinoid tumors, and possibly adenocarcinomas. In this study, we characterized the progression of gastric cancer in a novel mouse model of AIG....

Basilar arteries with experimental vasospasm were studies histochemically using a catecholamine fluorescence technique in 15 cats. Fluorescence microscopy of normal vessels revealed abundant catecholamine fluorescence in the adventitia and in close contact with the media, but none within the media. Experimental subarachnoid hemorrhage resulted in depletion of catecholamine fluorescence in the a...

Ethnomedicinal implies the usage of medicinal plants used by a group of people on account of their traditional knowledge and phytochemical means the individual chemical that plant contains. This review involves the ethnomedicinal and phytochemical perspectives of Pyrus communis Linn. In the “The Indian Materia Medica”, the common pear or gabbu gosha is considered as ‘Amritphale’ because of its ...

Abstract Chamomile ( Matricaria chamomilla L., Asteraceae) is one of the most important medicinal plants with antiphlogistic, spasmolytic, carminative, antibacterial and antimycotic properties. Thirty-one chloroplast markers were developed, optimised for high-resolution melting analysis. Subsequently, 23 M. accessions (247 individuals) complemented 2 individuals closely related species discoide...

The purpose of our study is to evaluate the T2 weighted sequence with multishot radial sampling (Radial Acquisition Multi-shot) also known as Multivane in Philips Healthcare, introduced by J.Pipe aim minimize motion artifacts Magnetic Resonance Imaging (MRI). In field prostate MRI useful non-cooperating patients and/or who, due their clinical conditions (such glaucoma, arrhythmia, and severe be...

The study was performed to check if the well-known intestinal spasmolytic effect of mebeverine is paralleled by any changes in intestinal transepithelial currents. The transepithelial potential difference related to ionic currents of the isolated rabbit distal colon wall was measured by means of Ussing's technique under control conditions and after gentle mechanical stimulation of intestinal ep...

The research work deals with the screening of ethanol and chloroform extracts of Pachyrrhizus erosus seeds for central nervous system (CNS) depressant activity. The Pachyrrhizus erosus seed is known to contain rotinoids, flavonoids and phenylfuranocoumarin derivatives as chemical components and is reported to have antifungal, antisecretory, insecticides, antibacterial and spasmolytic activity. ...

The Lippia alba (Mill.) N.E. Brown (Verbenaceae) species, has effects sedative, analgesic and spasmolytic properties. This study had as its main objective to evaluate the essential oil of L. alba (EOLa) effect and that of its main constituents, citral and limonene, over tracheal smooth muscle from Wistar rats. EOLa, citral and limonene promoted relaxation of tracheal smooth muscle in contractio...

The inhibitory action of 1, 2, 3-trihydroxybenzene (pyrogallol) on the activity of catechol-O-methyltransferase (COMT) is well known (1-4). Recently, 1, 3, 5,-trihydroxy benezene (phloroglucinol) and 2, 4, 6-trihydroxy-l-propiophenom~ (THPP) have been shown to exert spasmolytic action in experimental animals and to relieve spastic disorders of the urinary tract and biliary ducts in patients (5-...