This communication presents a novel and solvent-free method to synthesise Mg(B3H8)2 via the gas-solid reaction between B2H6 and Mg2NiH4, which overcomes the limitations of wet chemical methods requiring solvent removal.

BODIPY dyes have been synthesized under solvent-free or essentially solvent-free conditions, within about 5 minutes in an open-to-air setup by using a pestle and mortar, with yields that are comparable to those obtained via traditional routes that typically require reaction times of several hours to days.

A highly efficient, simple and clean solvent-free protocol for the synthesis of polyhydroquinolines is described. The one-pot multi-component condensation reaction between arylaldehydes, dimedone (5,5-dimethylcyclohexane-1,3-dione), β-ketoesters and ammonium acetate in the presence of catalytic amount of (2.5 mol%) melamine trisulfonic acid (MTSA) as a recyclable, green and attractive sulfonic ...

A  convenient  and  efficient  one-pot  four-component  synthesis  of  1,  2,  4,  5-tetrasubstituted  imidazoles  using  nano  TiO2  as  a  recyclable  catalyst  is  reported.  The results  show  that  the  methodology  has  several  advantages  such  as  low  loading  of catalyst,  excellent  yield,  short  reaction  time,  operational  simplicity  and  solvent-free conditions.

In the present of methylimidazolium hydrogen sulfate, the synthesis of arylidene heterobicyclic pyrimidinones is studied by condensation of aromatic aldehyde, cyclopentanone, and urea or thiourea. Using solvent-free conditions, non-toxic and inexpensive materials, simple and clean work-up, short reaction times and good yields of the products are the advantages of this method.

A simple and mild method for tetrahydropyranylation of alcohols is reported at room temperature using a catalytic amount of 3-methylimidazolinium hydrogensulfate([Hmim]HSO4) as a green, efficient and reusable catalyst. Using solvent-free conditions, non-toxic and inexpensive materials, modest and clean work-up, short reaction times and high yields of the products are the advantages o...

A phosgene-free synthesis of symmetrical N,N'-disubstituted urea by the reaction of aromatic and aliphatic primary amines and urea promoted by  microwave irradiation in the presence of a suitable energy-transfer solvent such as N-N-dimethylacetamide is described.

A novel method for oxazine derivatives formation is established using the reaction of ammonium thiocyanate and acid chlorides with 1-naphthol in the presence of Nanoparticle of ZnO to afford [1,3]oxazine-4-thione derivatives under solvent-free conditions at room temperature in excellent yields. 

In this study, an efficient and green process for the synthesis of dihydropyrimidin-2(1H)-ones from aromatic benzaldehydes, ethyl acetoacetate and urea using Al-MCM-41 as heterogeneous catalyst and microreactor under solvent-free conditions has been developed. The advantages of this method are easy work-up procedure, regeneration of the catalyst, clean and neutral reaction conditions.