The study of diffusion in macromolecular solutions is important in many biomedical applications such as separations, drug delivery, and cell encapsulation, and key for many biological processes such as protein assembly and interstitial transport. Not surprisingly, multiple models for the a-priori prediction of diffusion in macromolecular environments have been proposed. However, most models inc...

The high-dilution diffusion coefficients of K+, Rb+ , Cs+, and T1+ in molten LiN03—KN03 mixtures are measured over a wide range of temperatures and concentrations by means of wavefront-shearing interferometry. A slightly positive deviation from linearity is found for the concentration dependence of the diffusion coefficient of K + , Rb+ , and T1+, while no deviation is found for Cs+ within the ...

Diffusion coefficients, D, for ethanol in supercritical carbon dioxide (scCO2) were measured the temperature range 306.15–331.15 K and along 10.5 MPa isobar, using Taylor dispersion technique. The obtained diffusivities ranged from 1.49 × 10?8 to 2.98 m2 s?1, an order of magnitude higher than usual liquids. dependence D on solvent density was examined. Various correlation models based hydrodyna...

Background: In recent years, drug resistance to human pathogenic fungi has been increased. Medicinal plants are one way to overcome antibiotic resistance. The aim of this study was to evaluate the antifungal and inhibitory activity of five medicinal plants on the growth of Candida albicans. Methods: This study was done in the Microbiology Lab of Shahid Bahonar University of Kerman, Iran in 2...

Sorption and permeation of several organic vapours in poly(dimethylsiloxane) were investigated. Solubility and permeability coefficients measured show a strong dependence of the applied vapour activity typical for these systems, contrary to the behaviour of permanent gases. However, as irregularities in the series of chloromethanes show, highest sorption does not necessarily lead to the highest...

The Vrentas/Duda proposal for the diffusion of polymer-solvent systems, which is based on the free-volume theory, was employed in correlating and predicting mutual diffusion coefficients in highly concentrated polymer solutions. It has been observed that the predictive version of the model is capable of qualitatively representing the experimental data, while the use of an adjustable parameter g...

Attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy has been used to investigate the effects of three fatty acid esters on skin permeation. Propylene glycol diperlargonate (DPPG), isopropyl myristate (IPM) and isostearyl isostearate (ISIS) were selected as pharmaceutically relevant solvents with a range of lipophilicities and cyanophenol (CNP) was used as a model dru...

Long-timescale molecular dynamics simulations (300 ns) are performed on both the apo- (i.e., camphor-free) and camphor-bound cytochrome P450cam (CYP101). Water diffusion into and out of the protein active site is observed without biased sampling methods. During the course of the molecular dynamics simulation, an average of 6.4 water molecules is observed in the camphor-binding site of the apo f...

This work described a simple and efficient method for the synthesis of 1-azabicyclo[3.1.0]hexane-3-ene derivatives. arylidenmalononitriles and hydroxylamine hydrochloride in the presence of NaOH, under microwave irradiation and solvent-free conditions produced the titled compounds in good to excellent yields. Using of simple chemicals, short reaction times, and solvent-free conditions, high yie...