BACKGROUND Even after adequate immunosuppression therapy, acute rejection continues to be the single most important cause of graft dysfunction after renal transplantation. Renal allograft biopsy continues to be the reference standard, though certain clinical and biochemical parameters are helpful in assessment of these patients. Renal allograft rejection is mediated by T lymphocytes, expressing...

INTRODUCTION Syndecan-1 (Sdc1; CD138) is a major transmembrane heparan sulfate proteoglycan expressed on the extracellular, luminal surface of epithelial cells and syncytiotrophoblast, thus comprising a major component of the glycocalyx of these cells. The "soluble" (shed) form of Sdc1 has paracrine and autocrine functions and is normally produced in a regulated fashion. We compared plasma solu...

BACKGROUND & OBJECTIVES Platelet endothelial cell adhesion molecule-1 (PECAM-1) plays a key role in the transendothelial migration of circulating leukocytes (diapedesis) during vascular inflammation. We hypothesized that genetic variation and the level of soluble PECAM-1 could be associated with the development of atherosclerosis and conducted a study on gene polymorphisms of PECAM-1 and solubl...

BACKGROUND AND PURPOSE Activation of endothelial cells is a consequence of cerebral ischemia and leads to the expression of adhesion molecules such as intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin, which can be released into the blood. This study aimed to define the kinetics of soluble adhesion molecule serum levels after cerebral ischemi...

In this article, we consider control of fusion, quotients, and p-soluble fusion systems. For control of fusion, we prove the three main theorems in the literature in a new, largely elementary way, significantly shortening their proofs. To prove one of these, and a theorem of Aschbacher that the product of strongly closed subgroups is strongly closed, we produce a consolidated treatment of quoti...

Increased numbers of CD146-bearing circulating endothelial cells (CECs) in the peripheral blood probably represent the most direct evidence of endothelial cell damage. As acute ischaemic strokes are associated with endothelial abnormalities, we hypothesised that these CECs are raised in acute stroke, and that they would correlate with the other indices of endothelial perturbation, i.e. plasma v...

Phosphorus solubilizing microorganisms are capable of transforming insoluble phosphorus (P) forms to soluble and bioavailable P. The aim of the present study was to isolate P solubilizing bacteria from forest soils around the rock phosphate (RP) mine of Koh-e-SepidLar in Kohgiluyeh and Boyer Ahmad province and evaluate their ability in Sperber culture medium and wheat straw medium in the presen...