BACKGROUND The term solitary fibrous tumor (SFT) is preferred over meningeal hemangiopericytoma (HPC), because NAB2-STAT6 gene fusion has been observed in both intracranial and extracranial HPCs. HPCs are now considered cellular variants of SFTs. METHODS This study analyzes 19 patients with STAT6-confirmed SFTs, who were followed for over 11 years in a single institution. Ten patients (10/19,...

INTRODUCTION Renal solitary fibrous tumors (SFTs) are spindle cell neoplasms of mesenchymal origin, and very rare with only 46 cases reported worldwide to date. It is crucial to differentiate this tumor from other tumors of the kidney, so as to avoid unnecessary treatment. Therefore, our objective was to review reports of renal SFTs, their clinical presentations, imaging methods, and surgical m...

BACKGROUND/AIMS The calcifying fibrous tumor (CFT) is classified as a benign fibrous lesion, and it is a rare pathologic entity. We evaluated the feasibility, efficacy and safety of endoscopy treatment for CFT. MATERIALS AND METHODS We retrospectively analyzed a total of 4 gastric CFTs that were treated with ESD or EFR at the endoscopic center of Zhongshan Hospital, Fudan University, in Shang...

-Abstract=We report here 6 cases with classical forms of nonossifying fibroma (NOF) and 1 case of fibrous cortical defect (FCD) which occurred in the metaphysis of the long bones of children along with 2 cases of fibrous histiocytoma (FH) which occurred in the veretebra and femur neck of adults. Their clinical data, radiographs, histopathology, and ultrasturctural features are described. Throug...

OBJECTIVES/HYPOTHESIS Head and neck solitary fibrous tumors (SFTs) are quite rare, with <200 cases reported in the literature. The purpose of this study was to analyze the diagnostic and therapeutic challenges of this rare disease while reporting the largest head and neck case series. STUDY DESIGN Retrospective review. METHODS Between 1991 and 2011, 13 cases of head and neck SFTs from the p...

Cancer stem cells (CSCs) are hypothesized as tumor-initiating cells within tumors and main contributors of tumor growth, metastasis and recurrence. Mammary cancer cells, MCF-7 cells, were cultured on 3D polycaprolactone (PCL) fibrous scaffolds, showing an increased proportion of CSCs. The expression of stem cell markers, including OCT3/4 and SOX2, and breast CSC-specific markers, SOX4 and CD49f...

Solitary fibrous tumor has a wide spectrum of histopathologic features and many tumors show similar microscopic features. This similarity poses diagnostic challenges to the pathologists and immunohistochemical analysis is required in many cases. Moreover, it is a rare entity in orofacial region which consequently would make its diagnosis more challenging in oral cavity. The knowledge of various...

We herein describe the case of a 51-year-old male who presented with a mass of the epigastric region. Preoperative contrast enhanced abdominal computerized tomography revealed a solid mass between the left liver lobe and stomach. Histopathologic examination diagnosed the mass as a solitary fibrous tumor. Although solitary fibrous tumors are rare, especially in the abdomen of adults, they are ge...