objective(s): comparative in vivo studies were carried out to determine the adsorption characteristics of amitriptyline (amt) on activated charcoal (ac) and sodium polystyrene sulfonate (sps). ac has been long used as gastric decontamination agent for tricyclic antidepressants and sps has showed to be highly effective on in-vitro drugs adsorption. materials and methods: sprague-dawley male rats...

nabro3 combined with nh4cl is found to be an efficient reagent for the transformation of sulfides into sulfoxides in aqueous and under mild conditions.

two sensitive spectrophotometric methods are presented for the assay of pantoprazole sodium sesqui hydrate (pnt) in bulk drug and in formulations using n-bromosuccinimide (nbs) and two dyes, methyl orange and indigo carmine, as reagents. the methods involve the addition of a known excess of nbs to pnt  in acid medium, followed by determination of unreacted oxidant by reacting with a fixed amoun...

background: the objective of this study is to develop a new animal model based on signaling pathways to understand the pathophysiology, therapy of depression, and to investigate the antidepressant activity of enicostemma littorale which is not yet established. methods: animal models of depression were raised by physical methods and administration of methyl isobutyl ketone (100 mg/kg b.w., i.p.,...

objective simple febrile seizures are the most common form of childhood seizures,often recurring within the first twenty-four hours. this study was conducted to determine the probable role of low serum  sodium levels in predicting seizure recurrence in febrile children. materials & methods for the study, 226 patients with seizures, aged between 6 months to 5 years, were divided into 3 groups of...

introduction: various methods commonly used for cleaning and shaping root canals have not been successful in completely eradicating bacteria due to anatomic complexity and root canals irregularities. disinfecting the canals with intracanal irrigants in addition to proper cleaning and shaping can produce a successful outcome. antimicrobials with sustained antibacterial activity would be desirabl...

conclusions it became clear at the end of the study that the effectiveness of two drugs were the same and they didn’t have any meaningful difference. according to the result gained from this study, levetiracetam is a proper alternative treatment instead of sodium valproate which has appropriate effectiveness along with lower complications. results comparison of mean generalized tonic colonic at...