A patient is reported with mast cell infiltration of the small intestine in the absence of the skin involvement characteristic of mast cell disease. She also had subtotal villous atrophy responsive to a gluten-free diet. Criteria for diagnosing mast cell disease of the small intestine are proposed. The literature of small intestinal mast cell disease is reviewed and the relationship to coeliac ...

BACKGROUND Intestinal malabsorption in the elderly is infrequent, and clinical features are muted so that the diagnosis is often missed. Physiologic changes with aging are restricted to altered absorption of calcium and perhaps zinc and magnesium; however, achlorhydria can lead to impaired absorption of vitamin B(12), folic acid, and calcium. METHODS AND RESULTS Small bowel bacterial overgrow...

Intestinal stem cells (ISCs) are a group of rare cells located in the intestinal crypts which are responsible for the maintenance of the intestinal homeostasis and intestinal regeneration following injury or inflammation. Lineage tracing experiments in mice have proven that ISCs can repopulate the entire intestinal crypt. It is noteworthy that in such experiments, only a subset of intestinal cr...

Two-thirds of patients with dermatitis herpetiformis have been found to have a flat or convoluted mucosa but no special association has been found in the other dermatoses studied with structural alterations in the small bowel mucosa. The frequency distribution of the predominant and individual small intestinal mucosal features is the same in the patients in the present series with eczema, psori...

conclusion most cte findings correlated with cdai and crp in patients with active crohn’s disease. background the accurate evaluation of crohn’s disease activity is important for the treatment of the disease and for monitoring the response. computerized tomography (ct) enterography is a useful imaging modality that reflects enteric inflammation, as well as extramural complications. objectives t...

Chronic nonspecific multiple ulcers of the small intestine is a rare but distinct clinical condition, characterized by multiple small intestinal ulcers of nonspecific histology and chronic, persistent gastrointestinal bleeding without nonsteroidal anti-inflammatory drug use. However, because of the term "nonspecific" in its nomenclature, some gastroenterologists have misinterpreted the disease ...

The field of radiological small-bowel imaging is changing rapidly, as is small-bowel enteroscopy. New techniques allow the depiction of intraluminal, mural, and extraintestinal features of various small-bowel disorders, such as Crohn's disease, small-bowel polyposis syndromes, small-intestinal malignancies, and coeliac disease. For patients in need of repeated small-bowel imaging, modalities th...