patients with keratoconus constitute a large proportion of patients suffering from anterior segment disorders. as of this time, however, its pathogenesis has not yet been elucidated. a reduction in cross-link between collagen molecules has been observed in keratoconic eyes as compared to normal ones. present approaches only address refractive errors resulting from the abnormal abnormal corneal ...

Researchers predict that the ``scattering matrix'' of a collection particles could be used to slow down, potentially allowing for cooling significantly more than is possible with current techniques.

Words that are more predictable given a previous context show facilitated processing over low predictable ones. Such facilitation has been traditionally viewed as associated with reduced amplitudes in the N400 component. However, this effect is observed during the presentation of the target word, and it does not provide direct information about the prediction processes engaged before. To overco...

UNLABELLED Slow-wave oscillations, the predominant brain rhythm during sleep, are composed of Up/Down cycles. Depolarizing Up-states involve activity in layer 5 (L5) of the neocortex, but it is unknown how diverse subtypes of neurons within L5 participate in generating and maintaining Up-states. Here we compare the in vivo firing patterns of corticopontine (CPn) pyramidal cells, crossed-cortico...

The spread of rumors, which are known as unverified statements of uncertain origin, may threaten the society and it's controlling, is important for national security councils of countries. If it would be possible to identify factors affecting spreading a rumor (such as agents’ desires, trust network, etc.) then, this could be used to slow down or stop its spreading. Therefore, a computational m...

Glycation is a protein modification, which results in a change in a protein structure. Glycation is believed to be the etiology of various age-related diseases such as diabetes mellitus and Alz-heimer’s disease (AD). Activation of microglia and resident macrophages in the brain by glycated proteins with subsequent oxidative stress and cytokine release may be an important factor in the progressi...

Slow oscillatory activity (<1 Hz) is observed in vivo in the cortex during slow-wave sleep or under anesthesia and in vitro when the bath solution is chosen to more closely mimic cerebrospinal fluid. Here we present a biophysical network model for the slow oscillations observed in vitro that reproduces the single neuron behaviors and collective network firing patterns in control as well as unde...