Skin loss is one of the oldest and still not totally resolved problems in the medical field. Since spontaneous healing of the dermal defects would not occur, the regeneration of full thickness of skin requires skin substitutes. Tissue engineering constructs would provide a three dimensional matrix for the reconstruction of skin tissue and the repair of damage. The aim of the present work is to ...

IMPORTANCE Acellular dermal matrices have many current and potential applications, but their long-term safety has not been extensively studied. In particular, limited information exists regarding such materials' resistance to infection. OBJECTIVE To assess the resistance to microbial penetration of common acellular dermal matrix materials used in reconstruction after skin cancer excision, tre...

world production of caviar from the farmed sturgeon has recently so increased that in addition to compensate reduction of natural resources of sturgeon, it has also increased its share in the world market for caviar and its substitutes. although belarus, china and norway are currently considered as the main exporting countries of caviar and its substitutes but, iran solely exports caviar from s...

A previously developed fibrin-agarose skin model—UGRSKIN—showed promising clinical results in severely burnt patients. To determine the histological parameters associated to biocompatibility and therapeutic effects of this model, we carried out a comprehensive structural ultrastructural study UGRSKIN grafted patients after 3 months follow-up. The epidermis was analogue native human from day 30t...

Background. The use of skin substitutes as temporary or permanent coverings has been a subject of research and study since 1500 BC. Temporary coverage of the burn wound can decrease the metabolic rate, fluid loss, pain, and colonization. The aim of this study is to review clinical experience with Biobrane and aldehyde-treated porcine skin (E.Z. Derm) as biosynthetic skin substitutes for the tre...