We already reported that genetically engineered resveratrol-enriched rice (RR) showed to down-regulate skin melanogenesis. To be developed to increase the bioactivity of RR using calli from plants, RR was adopted for mass production using plant tissue culture technologies. In addition, high-pressure homogenization (HPH) was used to increase the biocompatibility and penetration of the calli from...

Introduction The skin barrier function is a major challenge for delivery of drugs via the skin. Located in the outermost layer of the skin, the stratum corneum (SC) consists of dead cells embedded in lipid regions, only 10–20 µm thick, tough but flexible and elastic. Hypodermic needles penetrate the skin succesfully, but nerve rich tissue in the lower skin is penetrated which is simply painfull...

This study evaluated the potential for bacterial contamination of saline nasal spray/drop solution after 3 days of clinical use in patients. Twenty patients with upper respiratory infection used the saline as a spray, and 20 patients used the solution as drops. Bacterial growth was present in 18 (907%) solution containers of the spray group and in 3 (157%) solution containers of the drops group...

OBJECTIVES To evaluate infection control and the incidence of bacterial pathogens in Emergency Medical Service (EMS) ambulances in Riyadh, Saudi Arabia. The effectiveness of fumigation techniques used for these ambulances to minimize the spread of infection to transported patients and pre-hospital care providers was also assessed. METHODS Based on previous literature review indicating a highe...

AIMS To determine the frequency, characteristics and risk factors of cardiac device infections in the Isala Hospital. METHODS We retrospectively studied all patients who underwent cardiac device procedures performed in the cardiac catheterisation lab and the operating room from 2010 to 2012. All patients who developed a cardiac device infection were reviewed for its characteristics. RESULTS...

Macaronesia, which includes five mid-Atlantic archipelagos (Azores, Madeira, Selvagems, Canaries, and Cape Verdes), has been traditionally recognized as a distinct biogeographic unit whose circumscription has been intimately associated with the hypothesis that the flora is a relict of a formerly broadly distributed subtropical Tertiary flora. The concept of Macaronesia is revisited here using p...