The skin possesses qualities that make it desirable for gene therapy, and studies have focused on gene therapy for multiple cutaneous diseases. Gene therapy uses a vector to introduce genetic material into cells to alter gene expression, negating a pathological process. This can be accomplished with a variety of viral vectors or nonviral administrations. Although results are promising, there ar...

Retinoids (vitamin A and its metabolites) are potent natural regulators of cellular activities, including cell growth and differentiation, and they mediate many essential regulatory functions, especially in the skin. Biologically active retinoids exert their effects by binding to nuclear retinoic acid receptors and retinoid-X-receptors. The group of pharmacologically used retinoids include natu...

(Pp. 116. 57s. per volume.) Amsterdam: Elsevier (Agents, D. van Nostrand, 358 Kensington High Street, London, W.14), 1959. "EPILEPSIA," which is the oflicial organ of the "International League against Epilepsy," has, until March, 1959, been published once a year, but it is now under a new editorial board, and they intend to publish the new "Epilepsia" quarterly. As the editors point out, it wil...

The Korean list of occupational skin diseases was amended in July 2013. The past list was constructed according to the causative agent and the target organ, and the items of that list had not been reviewed for a long period. The revised list was reconstructed to include diseases classified by the International Classification of Diseases (10th version). Therefore, the items of compensable occupa...

The tegumentary system becomes a scenario for immune responses. The knowledge of these conditions has led to induction of complementary animal models, better knowledge of the pathophysiology, and new tools [1] for diagnosis and therapy of these autoimmune skin disorders. In this special issue from Autoimmune Diseases we have invited several papers to address the dermatological issue. One paper ...

Synonyms.?Bengal (Hong Kong, Singapore, etc.) rot, mango-toe, athlete's foot and foot tethers are synonyms for ringworm of the foot. The disease is caused by a fungus, chiefly the Epidermophyton fioccosum, and the nidus of infection is usually the feet, between the toes, especially the fourth and fifth toe, and the groin area. From the toes the infection spreads to the other parts of the foot a...

GARDINER'S HANDBOOK OF SKIN DISEASES. Fourth Edition, revised. By John Kinnear, M.D., M.R.C.P. 239 pages; i6 Colour Plates; 70 Illustrations. E. & S. Livingston, I939. Price, ios. 6d. THIS handbook sets out to describe briefly the more common diseases of the skin and succeeds in presenting a satisfactory introduction to the subject. In a work of this size, more than a passing reference to some ...

As mental and psychological issues are important in the development of many dermatologic diseases, these factors are of special interest in research. Psychoneuroimmunology is the study of interaction between psychological processes and the nervous and immune systems of the human body, and it was comprehensively described for the first time about 30 years ago. Communication between the mind and ...