Abstract Background Early mechanisms underlying the progressive tissue death and regenerative capability of burn wounds are understudied in human skin. A clinically relevant, reproducible model for wound healing is needed to elucidate early changes environment. This study reports a contact on skin that explores extent injury over time, defines inter-individual variability enable use mechanistic...

Background: Thermal wounds are relatively uncommon in veterinary practice and most of them are the result of accidental burns. Patients with severe burns are among the most challenging cases presented to veterinarians, because severe burn injury leads to significant hemodynamic instability, massive fluid shifts, and hypovolemia requiring prompt and aggressive therapy. Because severe burn injury...

 Toxic by all routes of exposure – inhalation, ingestion, skin contact  Carcinogenic in humans  Inhalation of vinyl chloride causes coughing, wheezing and breathlessness, headache, ataxia, drowsiness and coma  Ingestion of vinyl chloride causes nausea, vomiting, diarrhoea, abdominal pain, and haematemesis may occur.  Skin contact causes irritation, pain, burns and contact dermatitis. Rapid...

We describe the case of a two-year-old boy with massive burns. After the period of shock and sepsis, very successful four-phase operative treatment was performed, with combined skin grafting homograft plus autograft. With regard to the four surgical interventions, in the first two we used the above combined method, while in the other two we used grafting only with skin autograft. We also used t...