This paper presents an analytical study of electroosmotic (EO) pumps with porous pumping structures. We have developed an analytical model to solve for electroosmotic flow rate, pump current, and thermodynamic efficiency as a function of pump pressure load for porous-structure EO pumps. The model uses a symmetric electrolyte approximation valid for the high-zeta-potential regime and numerically...

Dear Editor, We thank Aubeeluck, Buchanan and Stupple (ABS) for their comments [23] regarding our recent paper on the psychometric properties of the Huntington’s Disease Quality of Life Battery for Carers (HDQOL-C) and the Alzheimer’s Carers Quality of Life Inventory (ACQLI) among carers of people with Huntington’s disease (HD) [1], and the Editor for providing us with this opportunity to clari...

The promise of microarray technology in providing prediction classifiers for cancer outcome estimation has been confirmed by a number of demonstrable successes. However, the reliability of prediction results relies heavily on the accuracy of statistical parameters involved in classifiers. It cannot be reliably estimated with only a small number of training samples. Therefore, it is of vital imp...

Stormwater suspended solids typically are quantified using one of two methods: aliquot/subsample analysis (total suspended solids [TSS]) or whole-sample analysis (suspended solids concentration [SSC]). Interproject comparisons are difficult because of inconsistencies in the methods and in their application. To address this concern, the suspended solids content has been measured using both metho...

Adsorption at surfaces can be modelled using a periodic supercell approach or using finite clusters. For many systems and properties these models are complementary and often the most productive way to work is to use a combination of these techniques. If reliable data is to be obtained it is essential that convergence is achieved with respect to the size of supercell and cluster. This work discu...

SUMMARY With advances in medical research, effective treatments are becoming standard of care for many diseases. Consequently, when testing a new treatment, the sample size in a clinical trial is on the rise in order to demonstrate a moderate, yet clinically meaningful, improvement in therapeutic effect (compared to an active control), which often makes it impossible to enroll all patients from...

In this paper we examine the usefulness of two sample size invariant measures for the comparative analysis of author productivity Most of the studies which have been carried out on modeling the quantitative structure of author productivity are mainly concerned with describing the given samples and little e ort has been devoted to clarifying the statistical status of the sample However author pr...

CONTEXT Egger's regression test is often used to help detect publication bias in meta-analyses. However, the performance of this test and the usual funnel plot have been challenged particularly when the summary estimate is the natural log of the odds ratio (lnOR). OBJECTIVE To compare the performance of Egger's regression test with a regression test based on sample size (a modification of Mac...

BACKGROUND This article presents a meta-analysis of thalamic size reduction in schizophrenia. METHODS Reviewed studies were based on magnetic resonance imaging or postmortem material and included measures of thalamic volume or thalamic area in schizophrenic patients and comparison subjects. Meta-analysis I was based on absolute thalamic values (not controlled for overall brain size), and Meta...