نتایج جستجو برای: single strand break

تعداد نتایج: 927558  

Journal: :Nucleic Acids Research 2006
Naoyuki Sarai Wataru Kagawa Takashi Kinebuchi Ako Kagawa Kozo Tanaka Kiyoshi Miyagawa Shukuko Ikawa Takehiko Shibata Hitoshi Kurumizaka Shigeyuki Yokoyama

The process of homologous recombination is indispensable for both meiotic and mitotic cell division, and is one of the major pathways for double-strand break (DSB) repair. The human Rad54B protein, which belongs to the SWI2/SNF2 protein family, plays a role in homologous recombination, and may function with the Dmc1 recombinase, a meiosis-specific Rad51 homolog. In the present study, we found t...

Journal: :Cell 2008
Ben B. Hopkins Tanya T. Paull

The Mre11/Rad50 complex has been implicated in the early steps of DNA double-strand break (DSB) repair through homologous recombination in several organisms. However, the enzymatic properties of this complex are incompatible with the generation of 3' single-stranded DNA for recombinase loading and strand exchange. In thermophilic archaea, the Mre11 and Rad50 genes cluster in an operon with gene...

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