We compare the SNP-based and gene-based association studies using 697 unrelated individuals. The Benjamini-Hochberg procedure was applied to control the false discovery rate for all the multiple comparisons. We use a linear model for the single-nucleotide polymorphism (SNP) based association study. For the gene-based study, we consider three methods. The first one is based on a linear model, th...

The interaction between the single-stranded DNA and the homologous duplex DNA is essential for DNA homologous repair. Here, we report that parallel triplex structure can form spontaneously between a mechanically extended ssDNA and a homologous dsDNA in protein-free condition. The triplex has a contour length close to that of a B-form DNA duplex and remains stable after force is released. The bi...

Introduction: This paper analyses the ability of single-photon avalanche diodes (SPADs) for neural imaging. The current trend in the production of SPADs moves toward the minimumdark count rate (DCR) and maximum photon detection probability (PDP). Moreover, the jitter response which is the main measurement characteristic for the timing uncertainty is progressing. Methods: The neural imaging pro...

Nowadays carbon nanoparticles are applied on the island of single electron transistor and Nano-transistors. The basis of single electron devices (SEDs) is controllable single electron transfer between small conducting islands. Based on the important points in quantum mechanics, when a wave passes through several spatial regions with different boundaries, the wave function of the first region di...

remotely sensed imagery is proving to be a useful tool to estimate water depths in coastalzones. bathymetric algorithms attempt to isolate water attenuation and hence depth from other factors byusing different combinations of spectral bands. in this research, images of absolute bathymetry using twodifferent but related methods in a region in the southern caspian sea coasts has been produced. th...

the physical adsorption of hydrogen sulfide and carbon dioxide gases on the zigzag (5,0) carbon nanotubes doped with nitrogen was investigated through the application of b3lyp/6-31g* at the level of theory on gaussian 03 software. a variety of stable and high abundance structures of nitrogen doped carbon nanotubes were considered in order to study the interaction between the mentioned gases in ...

in this paper, the effect of surface area of reaction layers in gas diffusion electrodes on oxygen reduction reaction was investigated. for this purpose, various amounts (0.1, 0.2, 0.3, 0.4, 0.5, 1, 1.5 and zero %wt of total loading of reaction layer) of single walled carbon nanotube (swcnt) were inserted in the reaction layer. the performance of gas diffusion electrodes for oxygen reduction re...

in this paper we have down three theoretical study by using monte carlo simulation and mm+,amber and opls force field. the calculations were carried out using hyper chem professional,release 7.01 package of program. first we have studied the interaction of h2 molecule and he atomwith single-walled carbon nanotube at different temperature. for doing this study we placed h2 andhe in the center an...

conclusions consequently, this study shows promising results for il of single implants, and it can be considerable that treatment with microtextured surface implants is a predictable and appropriate method of treatment. background the immediate loading (il) protocol has gained increased popularity among surgeons in the last decade. objectives this study aimed to evaluate the clinical performanc...

human immunodeficiency virus (hiv) infection is the major problem in the world. nowadays, new anti-retroviral drugs are extracted from medicinal plants, make an important role to supersede synthetic drugs with different side effects. in this study, we studied the salix aegyptiaca l extract, iranian herb, as an anti-hiv drug with anti-retroviral effects. we used a single cycle replicable (scr) h...