The phenolic compounds in eggplant offer potential natural antioxidants for improved health. A large number of samples were examined order to find germplasm with a high health promotion. genome-wide association study (GWAS) was conducted identify single nucleotide polymorphisms (SNPs) associated variations total content (TPC) and antioxidant activity eggplants, including ABTS (2,2′-azino-bis(3-...

Caenorhabditis elegans is an important experimental organism for the study of recombination during meiosis. Here, we provide methods for the use of single-nucleotide polymorphisms (SNPs) for the study of crossing over in C. elegans.

Recent advances in DNA sequencing techniques have led to an increase in the identification of single nucleotide polymorphisms (SNPs) in BRCA1 and BRCA2 genes, but no further information regarding the deleterious probability of many of them is available (Variants of Unknown Significance/VUS). As a result, in the current study, different sequence- and structure-based computation...

Single nucleotide polymorphisms (SNPs) in TERT may be associated with susceptibility to esophageal cancer. In this study, we analyzed the association between TERT SNPs and risk of esophageal cancer in 386 esophageal cancer patients and 495 healthy subjects from the Xi'an area of China. Of the four SNPs examined, rs10069690 and rs2242652 were correlated with esophageal cancer risk. Additionally,...

We determined whether single nucleotide polymorphisms (SNPs) in the glutathione S-transferase omega (GSTO) and arsenic(III)methyltransferase (AS3MT) genes were associated with concentrations of urinary arsenic metabolites among 900 individuals without skin lesions in Bangladesh. Four SNPs were assessed in these genes. A pathway analysis evaluated the association between urinary arsenic metaboli...

Population genetic research is a critical tool for the conservation and management of marine mammals other species. The bowhead whale (Balaena mysticetus) subject to aboriginal subsistence hunting in Alaska, Canada, Chukotka, Greenland managed by International Whaling Commission all those countries except Canada. Genetic studies support plans determination safe quotas providing information on l...

The adaptation of marine and anadromous fishes to novel, freshwater environments requires major physiological shifts in functions related osmoregulation, immunity, metabolism. For Atlantic salmon (Salmo salar) populations, such changes have occurred independently many landlocked populations that were formed as a result extensive hydrological North America around 10 000 years ago. We compared pa...

We developed a modified allele-specific PCR procedure for assaying single nucleotide polymorphisms (SNPs) and used the procedure (called SNAP for single-nucleotide amplified polymorphisms) to generate 62 Arabidopsis mapping markers. SNAP primers contain a single base pair mismatch within three nucleotides from the 3' end of one allele (the specific allele) and in addition have a 3' mismatch wit...

BACKGROUND We studied the association between iron intake and polymorphisms in the iron transporter gene SLC40A1 and the risk of tuberculosis. METHODS We compared iron intake, the frequency of SLC40A1 mutations, and interactions among these variables among 98 tuberculosis patients and 125 controls in Kwazulu-Natal, South Africa. RESULTS Four SLC40A1 single-nucleotide polymorphisms (SNPs) we...

Background: Tumor necrosis factor- a (TNF-α) is a cytokine that was identified as a factor with a wide range of proinflammatory activities. The expression of bovine TNF-α in mammary tissue during pregnancy seems to have a role in development of the corresponding glands.Objective: Single nucleotide polymorphisms (SNPs) were defined in 3′-flanking region of...