The receptor for advanced glycation end products (RAGE) is a transmembrane protein that interacts with its ligands, (AGEs). AGEs are elevated in diabetes and diabetic complications, leading to increased oxidative stress activation of pro-inflammatory pathways facilitated by AGE–RAGE signaling. Polymorphisms the RAGE gene can potentially affect interaction downstream signaling, which plays cruci...

myostatin (mstn), also known as growth and differentiation factor-8 (gdf8), is a member of the transforming growth factor beta (tgf-?) superfamily that decreases growth in mammals. a single nucleotide polymorphism (snp) in the myostatin (gdf8) 3'utr of oar2 has been known as responsible for muscular hypertrophy in foreign breeds. in this study, in order to identify single nucleotide polymo...

background: hypospadias is one of the most common congenital abnormalities in the male which is characterized by altered development of urethra, foreskin and ventral surface of the penis. androgen receptor gene plays a critical role in the development of the male genital system by mediating the androgens effects. objective: in present study, we looked for new variations in androgen receptor pro...

We report the identification of two single nucleotide polymorphisms in Cannabis sativa L. that are associated with female and male plant sex phenotypes located on top arm X chromosome. High resolution melt analysis was used to develop validate a novel, rapid method for medical (or) recreational cannabis as well hemp. This can distinguish between dioecious (XY) (XX) plants 100% accuracy also be ...

Objective: NRG1 is one of the genes that was reported to have susceptibility alleles effecting phenotype schizophrenia. There are many SNPs (single nucleotide polymorphisms) located in gene with suspected which were associated In this study, we investigated potential associations between schizophrenia and polymorphisms rs4560751 rs3802160. Material Methods: We collected DNA samples 96 patients ...