Recent advances in single-cell, transcriptomic profiling have provided unprecedented access to investigate cell heterogeneity during tissue and organ development. In this study, we used massively parallel, single-cell RNA sequencing to define cell heterogeneity within the zebrafish kidney marrow, constructing a comprehensive molecular atlas of definitive hematopoiesis and functionally distinct ...

Laparoscopic live donor nephrectomy (DN) has been established as a useful alternative to the traditional open methods of procuring kidneys. To maximize the advantages of the laparoendoscopic single-site (LESS) method, we applied natural orifice specimen extraction to LESS-DN. A 46-year-old woman with no previous abdominal surgery history volunteered to donate her left kidney to her husband and ...

background: diagnosis of kidney scar could prevent vesico urethral reflax and its complications such as hypertension and renal failure. this study was conducted to determine average kidney length and volume in infants by sonography to accurate diagnosis of scars. methods: this study was conducted on infants with the history of uti who referred to imam reza hospital, kermanshah iran, for dmsa sc...

The effects of synthetic atrial natriuretic factor on renin secretion were examined in anesthetized dogs with either a single filtering kidney or a single denervated nonfiltering kidney. In dogs with a single filtering kidney (Series 1, n = 6), a priming dose of atrial natriuretic factor (2 micrograms/kg, i.v.) followed by sustained intravenous infusions at doses of 200 and 400 ng/kg/min for 20...

Denosumab is a human monoclonal antibody representing a novel therapy of osteoporosis. Contrary to always other antiosteoporotic drugs, it is not contraindicated in advanced chronic kidney disease, as its pharmacokinetic does not differ from patients with normal kidney function. However, published case reports in chronic kidney disease (CKD) patients stopped the therapy after single dose becaus...

For this, we obtained a fractal dimension of the proximal convoluted tubuli in the dog kidney by mean box-counting method. The fractal value we obtained is a flat dimension, and it is different than the line fractal dimension of the dog kidney arterial pattern, which was previously calculated by us (Gil et al., 2006). Thus, from optical microscopy images, we are able to obtain a single quantita...

Evaluation of kidney function by physical examination alone is imprecise and limited. Quantitative, reproducible assessment of kidney function requires laboratory measurements of substances in plasma and urine, followed by reliable interpretation. Thus, glomerular filtration, urine protein excretion, water metabolism, and electrolyte disturbances may be quantified. These data are very useful in...

This study aimed to investigate the impact of grafting using thin upper pole artery ligation for living-donor adult kidney transplantation. Few reports have examined the safety of thin upper pole artery ligation.Between January 2008 and May 2015, 613 consecutive living-donor adult kidney transplantations were performed. We excluded 21 recipients who experienced graft loss due to factors that we...

ABSTRACT The cardiorenal syndrome (CRS) is described as a multi-organ disease encompassing bidirectionally heart and kidney. In CRS type 4, chronic kidney (CKD) leads to cardiac injury. Different pathological mechanisms have been identified contribute the establishment of CKD-induced cardiomyopathy, including neurohormonal dysregulation, disturbances in mineral metabolism an accumulation uremic...

background and aims: infectious bronchitis virus (ibv) causes an acute, highly contagious respiratory and kidney disease of chickens which results in significant economic losses in commercial broilers, layers and breeders. rapid identification of ibv serotypes involved in respiratory complex is a problem in the differential diagnosis. materials and methods: in this study, a single and multiplex...