This paper considers the following sequence shu ing problem Given a biological sequence either DNA or protein s generate a random instance among all the permutations of s that exhibit the same frequencies of k lets e g dinucleotides doublets of amino acids triplets etc Since certain biases in the usage of k lets are fundamental to biological sequences e ective generation of such sequences is es...

Traditional approaches for homology detection rely on finding sufficient similarities between protein sequences. Motivated by studies demonstrating that from non-sequence based sources of biological information, such as the secondary or tertiary molecular structure, we can extract certain types of biological knowledge when sequence-based approaches fail, we hypothesize that protein-protein inte...

MUCH OF THE WORK IN THE data-mining community defines mining data as a collection of techniques for extracting knowledge out of large databases. This definition is a bit ambiguous because the “knowledge” extracted from databases varies dramatically across systems. In the spirit of intelligent systems, I suggest we define data mining roughly as a collection of techniques that produce representat...

The need to measure sequence similarity arises in information extraction, music mining, biological sequence analysis, and other domains, and often coincides with sequence alignment: the more similar two sequences are, the better they can be aligned. Aligning sequences not only shows how similar sequences are, it also shows where there are differences and correspondences between the sequences. T...

today, there arevarious statistical models for the discrete simulation of the rainfall occurrence/non-occurrence with more emphasizing on long-term climatic statistics. nevertheless, the accuracy of such models or predictions should be improved in short timescale. in the present paper, it is assumed that the rainfall occurrence/non-occurrence sequences follow a two-layer hidden markov model (hm...

conclusions the high prevalence of tet (o) resistance gene along with new detection of tet (a) resistance gene in campylobacter spp. isolated from poultry carcasses revealed an extensive tetracycline resistance among campylobacter isolates from poultry in iran. it emphasized the need for cautious use of tetracycline in poultry production to decrease the extension of tetracycline-resistant campy...

background: canine distemper (cd) is a lethal systemicdisease affecting a wide variety of terrestrial carnivores.objectives: this study was performed to survey epidemiologicaland molecular characteristics of the canine distemper virus(cdv) strains circulating in iran. methods: in this study, 19cdv-suspected unvaccinated dogs from northeast and center ofiran were analyzed for presence of cdv nuc...