Total knee arthroplasty (TKA) is associated with considerable postoperative pain. The relative analgesic efficacy and adverse effect profile of perioperative use of selective cyclooxygenase-2 (COX-2) inhibitors for patients undergoing TKA are unclear. This is a systematic review and meta-analysis of all randomized controlled trials evaluating perioperative administration of COX-2 inhibitors for...

BACKGROUND This study examines associations between perceptions of neighbourhood environment and physical activity and sports within Portuguese adolescents. METHODS The sample consisted of 4,877 individuals of both genders, with an average age of 14 years. The instrument used was the Health Behavior School-aged Children questionnaire. RESULTS Perceptions of the neighbourhood being unsafe fo...

BACKGROUND There is a small subgroup of patients with head and neck cutaneous squamous cell carcinoma (cSCC) in which nodal metastases present concurrently with the primary lesion. There is evidence that these tumors may represent a more aggressive subset of cSCC. The aim of this study was to determine whether alternative clinicopathologic prognostic factors should be applied to this patient co...

BACKGROUND The aims of this study are to evaluate the lip morphology and change of lip commissure after mandibular setback surgery (MSS) for class III patients and analyze association between the amount of mandibular setback and change of lip morphology. METHODS The samples consisted of 14 class III patients treated with MSS using bilateral sagittal split ramus osteotomy. Lateral cephalogram ...

The purpose of this study was to find efficacy values in playing microsituations in numerical equality with or without ball possession and to analyze the relation between these and the condition of winner or loser. The matches of the X World Championship of Water polo which did not end in a draw were analysed. Playing microsituations in numerical equality were evaluated by means of coefficients...

OBJECTIVE To evaluate the effects of an 8-month training program with standardized exercises on aerobic and anaerobic capacity in children and adolescents with cerebral palsy. DESIGN Pragmatic randomized controlled clinical trial with blinded outcome evaluation between July 2005 and October 2006. SETTING Participants were recruited from 4 schools for special education in the Netherlands. ...

Six abomasally-cannulated wethers (average initial weight 18 kg) were used in a split 3 X 3 Latin square design experiment with a crossover to determine effects of glucose (G) administered orally (O) or infused (I) into the abomasum on nitrogen metabolism and forage fiber digestion. Basal diets were Coastal bermudagrass (CBG) or CBG treated with 1% formaldehyde (F-CBG). Individual treatments we...

OBJECTIVE To determine whether blocking prolymphangiogenic factors such as vascular endothelial growth factor C (VEGF-C) would suppress alloimmunity in dry eye disease using a murine model. METHODS The effects of intraperitoneal injections of 400 μg of anti-VEGF-C antibody (treated group) and intraperitoneal normal saline (untreated group) were studied in murine dry eyes induced by exposing m...

Community–academic partnerships have demonstrated potential for studying and improving community and environmental health, but only recently have their policy impacts been systematically studied. This case study highlights the evolution, research, and policy processes and outcomes of a community based participatory research (CBPR) partnership that has had multilevel impacts on health policy con...